Skin cancer and HLA antigens - To the editor Journal Article
| Author: | Myskowski, P. L. |
| Article Title: | Skin cancer and HLA antigens - To the editor |
| Abstract: | To the Editor: The study by Bouwes Bavinck and colleagues on the relation between skin cancers and HLA antigens in renal-transplant recipients (Sept. 19 issue)1 offers further support to the notion that genetic background, immunologic responses, and environmental factors all contribute to the development of skin cancers in humans. Although the authors found an association between mismatching for HLA-B and an increased risk of squamous-cell carcinoma, they observed no such relation in the 18 patients with basal-cell carcinoma. The lack of an association between any HLA antigen and basal-cell carcinoma is not surprising, since the number of patients with this. © 1992, Massachusetts Medical Society. All rights reserved. |
| Keywords: | controlled study; human tissue; major clinical study; genetics; squamous cell carcinoma; cancer risk; note; letter; ultraviolet radiation; antigen expression; basal cell carcinoma; sun exposure; skin neoplasms; skin cancer; skin tumor; immunological tolerance; immunology; immune tolerance; hla matching; donor; hla antigen class 2; hla dr antigen; hla a antigen; carcinoma, basal cell; alloantigen; hla antigen; hla antigens; skin carcinogenesis; hla system; kidney transplantation; kidney graft; hla b27 antigen; human; priority journal; hla dr1 antigen; hla-dr1 antigen; allotype |
| Journal Title: | New England Journal of Medicine |
| Volume: | 326 |
| Issue: | 11 |
| ISSN: | 0028-4793 |
| Publisher: | Massachusetts Medical Society |
| Date Published: | 1992-03-12 |
| Start Page: | 765 |
| Language: | English |
| DOI: | 10.1056/nejm199203123261111 |
| PUBMED: | 1738388 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
