Diabetes and metabolic syndrome in survivors of childhood cancer Review

   


Authors: Novetsky Friedman, D.; Tonorezos, E. S.; Cohen, P.
Review Title: Diabetes and metabolic syndrome in survivors of childhood cancer
Abstract: Endocrine complications, including diabetes and metabolic syndrome, are highly prevalent in childhood cancer survivors. These metabolic derangements may contribute to survivors' risk of excess cardiovascular morbidity and premature mortality. This review summarizes existing knowledge on risk of diabetes and metabolic syndrome among childhood cancer survivors, focusing specifically on known risk factors, potential mechanisms, and screening recommendations. Early diagnosis via standardized risk-based screening can improve long-term outcomes in this population. Additional work is needed to elucidate the mechanisms underlying these metabolic complications and to inform the design of risk-reducing interventions and optimize long-term cardiometabolic health among survivors of childhood cancer. © 2018 S. Karger AG, Basel. All rights reserved.
Keywords: oncology; diabetes mellitus; insulin resistance; body composition; bone marrow transplantation; long-term follow-up; metabolic syndrome; endocrine dysfunction; metabolic disease
Journal Title: Hormone Research in Paediatrics
Volume: 91
Issue: 2
ISSN: 1663-2818
Publisher: S. Karger AG  
Date Published: 2019-06-01
Start Page: 118
End Page: 127
Language: English
DOI: 10.1159/000495698
PUBMED: 30650414
PROVIDER: scopus
PMCID: PMC6610586
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060212538&doi=10.1159%2f000495698&partnerID=40&md5=0d6d35b00f520f4d6ee2e168a27c7456
Notes: Review -- Export Date: 2 August 2019 -- Source: Scopus
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MSK Authors
  1. Danielle Novetsky Friedman
    110 Friedman
  2. Emily Tonorezos
    83 Tonorezos
  3. Paul Cohen
    3 Cohen
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