Author: | Livingston, P. O. |
Article Title: | Construction of cancer vaccines with carbohydrate and protein (peptide) tumor antigens |
Abstract: | Tumor vaccinology is as old as immunological thought and as young as our rapidly evolving understanding of antigen processing and presentation. The recent availability of carbohydrate and peptide tumor antigens suitable for vaccine construction, conjugate and recombinant vector technologies capable of augmenting helper and cytotoxic T cell activity and potent new immunological adjuvants have combined to produce considerable optimism for the future of tumor vaccines. © 1992. |
Keywords: | review; neoplasms; protein; drug development; peptide; tumor antigen; antigen presentation; antigens, neoplasm; cancer vaccine; immunogenicity; cytotoxic t lymphocyte; t-lymphocytes, cytotoxic; mycobacterium; cell activity; carbohydrate; vaccines; helper cell; virus vector; conjugation; adjuvant; gangliosides; ganglioside; recombinant dna technology; cancer; human; blood group antigen; blood groups |
Journal Title: | Current Opinion in Immunology |
Volume: | 4 |
Issue: | 5 |
ISSN: | 0952-7915 |
Publisher: | Elsevier Inc. |
Date Published: | 1992-01-01 |
Start Page: | 624 |
End Page: | 629 |
Language: | English |
DOI: | 10.1016/0952-7915(92)90038-g |
PUBMED: | 1418730 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 30 July 2019 -- Source: Scopus |