SUMO Takes Control of a Ubiquitin-Specific Protease Journal Article


Authors: Mohideen, F.; Lima, C. D.
Article Title: SUMO Takes Control of a Ubiquitin-Specific Protease
Abstract: In this issue of Molecular Cell, Meulmeester et al. (2008) identify USP25 as a SUMO2/3-interacting protein and substrate. A USP25 SUMO interaction motif directs SUMO2/3 specificity, and SUMO modification diminishes USP25's ability to bind and degrade polyubiquitin chains. © 2008 Elsevier Inc. All rights reserved.
Keywords: signal transduction; ubiquitin; protein function; protein motif; protein degradation; protein protein interaction; protein binding; amino terminal sequence; short survey; proteinase; protein structure; sumo protein; polyubiquitin; hydrolysis; isoprotein; amino acid motifs; protein modification; small ubiquitin-related modifier proteins; ubiquitin thiolesterase; conjugation; sumo 1 protein; protein sumo2; protein sumo3; ubiquitin specific protease 25
Journal Title: Molecular Cell
Volume: 30
Issue: 5
ISSN: 1097-2765
Publisher: Cell Press  
Date Published: 2008-06-05
Start Page: 539
End Page: 540
Language: English
DOI: 10.1016/j.molcel.2008.05.010
PUBMED: 18538649
PROVIDER: scopus
PMCID: PMC2753972
DOI/URL:
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "CODEN: MOCEF" - "Source: Scopus"
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  1. Christopher D Lima
    103 Lima