Authors: | Mohideen, F.; Lima, C. D. |
Article Title: | SUMO Takes Control of a Ubiquitin-Specific Protease |
Abstract: | In this issue of Molecular Cell, Meulmeester et al. (2008) identify USP25 as a SUMO2/3-interacting protein and substrate. A USP25 SUMO interaction motif directs SUMO2/3 specificity, and SUMO modification diminishes USP25's ability to bind and degrade polyubiquitin chains. © 2008 Elsevier Inc. All rights reserved. |
Keywords: | signal transduction; ubiquitin; protein function; protein motif; protein degradation; protein protein interaction; protein binding; amino terminal sequence; short survey; proteinase; protein structure; sumo protein; polyubiquitin; hydrolysis; isoprotein; amino acid motifs; protein modification; small ubiquitin-related modifier proteins; ubiquitin thiolesterase; conjugation; sumo 1 protein; protein sumo2; protein sumo3; ubiquitin specific protease 25 |
Journal Title: | Molecular Cell |
Volume: | 30 |
Issue: | 5 |
ISSN: | 1097-2765 |
Publisher: | Cell Press |
Date Published: | 2008-06-05 |
Start Page: | 539 |
End Page: | 540 |
Language: | English |
DOI: | 10.1016/j.molcel.2008.05.010 |
PUBMED: | 18538649 |
PROVIDER: | scopus |
PMCID: | PMC2753972 |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "CODEN: MOCEF" - "Source: Scopus" |