Current and future surgical approaches in the management of endometrial carcinoma Journal Article
| Author: | Leitao, M. M. Jr |
| Article Title: | Current and future surgical approaches in the management of endometrial carcinoma |
| Abstract: | The surgical approach to endometrial carcinoma has been and continues to be inconsistent. It ranges from hysterectomy alone for all patients, hysterectomy with lymphadenectomy based on the surgeon's criteria for risk of nodal metastasis based on preoperative grading and/or intraoperative assessments, and hysterectomy with limited lymphadenectomy, to hysterectomy with full pelvic and para-aortic lymphadenectomy for all patients. Recent evidence has clearly described the very poor correlation of pre- and/or intraoperative assessments with final hysterectomy pathologic findings. Lymphadenectomy has also been found to be therapeutic in high-risk groups. Despite this, many surgeons have not adopted a policy of comprehensive staging for all patients with endometrial carcinoma. All patients with endometrial carcinoma diagnosed on preoperative endometrial sampling should undergo comprehensive surgical staging if technically and medically possible. Surgical cytoreduction of metastatic disease is also associated with improved outcomes. © 2008 Future Medicine Ltd. |
| Keywords: | cancer survival; surgical technique; survival rate; overall survival; clinical trial; histopathology; review; cancer recurrence; advanced cancer; cancer risk; clinical trials as topic; cancer radiotherapy; disease free survival; postoperative care; cancer staging; recurrence risk; lymph node metastasis; endometrium carcinoma; hysterectomy; endometrial neoplasms; laparoscopy; cancer grading; diagnostic accuracy; laparoscopic surgery; laparotomy; preoperative evaluation; salpingooophorectomy; sentinel lymph node; lymph node excision; lymphadenectomy; treatment indication; surgical cytoreduction; cytoreductive surgery; medical decision making; morbidity; practice guideline; surgical approach; risk factor; high risk patient; risk assessment; cancer invasion; survival time; length of stay; hospitalization; intraoperative period; cancer size; operation duration; surgeon; surgical risk; brachytherapy; diagnostic error; metastasis potential; robotics; risk reduction; perioperative complication; endometrial carcinoma; radical hysterectomy; pelvic lymphadenectomy; uterus surgery; computer assisted surgery; molecular staging; panniculectomy; para-aortic lymphadenectomy |
| Journal Title: | Future Oncology |
| Volume: | 4 |
| Issue: | 3 |
| ISSN: | 1479-6694 |
| Publisher: | Future Medicine |
| Date Published: | 2008-06-01 |
| Start Page: | 389 |
| End Page: | 401 |
| Language: | English |
| DOI: | 10.2217/14796694.4.3.389 |
| PUBMED: | 18518764 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 7" - "Export Date: 17 November 2011" - "Source: Scopus" |
