Widespread changes in transcriptome profile of human mesenchymal stem cells induced by 2D nanosilicates Conference Paper

  


Authors: Carrow, J. K.; Cross, L. M.; Reese, R. W.; Jaiswal, M. K.; Gregory, C. A.; Kaunas, R.; Singh, I.; Gaharwar, A. K.
Title: Widespread changes in transcriptome profile of human mesenchymal stem cells induced by 2D nanosilicates
Conference Title: 42nd Annual Meeting and Exposition of the Society for Biomaterials
Abstract: Statement of Purpose: Two-dimensional (2D) nanomaterials, an ultrathin class of materials, have emerged as a new generation of materials due to their unique properties relative to macroscale counterparts. However, little is known about the transcriptome dynamics following exposure to these nanomaterials. Here we investigate the interactions of 2D nanosilicates, a layered clay, with human mesenchymal stem cells (hMSCs) at the whole transcriptome level by high-throughput sequencing (RNA-seq). © 2019 Omnipress - All rights reserved.
Keywords: cell culture; stem cells; transcriptomes; human mesenchymal stem cells; nanostructured materials; high-throughput sequencing; human mesenchymal stem cells (hmscs); macro scale; transcriptome profiles; two dimensional (2 d); ultra-thin
Journal Title Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume: 40
Conference Dates: 2019 Apr 3-6
Conference Location: Seattle, WA
ISBN: 1526-7547
Publisher: Society for Biomaterials  
Date Published: 2019-01-01
Start Page: 967
Language: English
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065430466&partnerID=40&md5=891d95192c0ed8d80121f407cd3c9668
Notes: Conference Paper -- Export Date: 3 June 2019 -- Source: Scopus