Author: | Shike, M. |
Article Title: | Copper in Parenteral Nutrition |
Abstract: | Copper is an essential nutrient for humans. Copper is a component of numerous enzymes that affect a wide variety of metabolic processes. Copper deficiency can result in anemia, neutropenia, skeletal abnormalities, and other clinical manifestations. There is no well-established laboratory measurement of body copper status. Copper supplementation is essential in parenteral nutrition to prevent an adverse effect of deficiency. Balance studies indicate that copper requirements in total parenteral nutrition amount to 0.3 mg/day in the adult. For children and infants, the estimated requirement is 20 μg/kg body wt/day. These amounts may have to be decreased in patients with cholestasis. © 2009 AGA Institute. |
Keywords: | clinical feature; neutropenia; disease association; anemia; melanin; heart disease; drug administration schedule; hemoglobin; practice guideline; dose-response relationship, drug; arthritis; burn; practice guidelines as topic; total parenteral nutrition; drug absorption; monophenol monooxygenase; dopamine; copper; cholestasis; amine oxidase (flavin containing); ceruloplasmin; copper zinc superoxide dismutase; dopamine beta monooxygenase; protein lysine 6 oxidase; copper blood level; copper deficiency; dopamine metabolism; hair discoloration; hypopigmentation; menkes syndrome; nutritional requirement; supplementation; wilson disease; deficiency diseases; nutritional requirements; parenteral nutrition; trace elements |
Journal Title: | Gastroenterology |
Volume: | 137 |
Issue: | 5 SUPPL |
ISSN: | 0016-5085 |
Publisher: | Elsevier Inc. |
Date Published: | 2009-11-01 |
Start Page: | S13 |
End Page: | S17 |
Language: | English |
DOI: | 10.1053/j.gastro.2009.08.017 |
PUBMED: | 19874945 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 30 November 2010" - "CODEN: GASTA" - "Source: Scopus" |