A prospective randomized trial of total parenteral nutrition after major pancreatic resection for malignancy Conference Paper

   


Authors: Brennan, M. F.; Pisters, P. W. T.; Posner, M.; Quesada, O.; Shike, M.
Title: A prospective randomized trial of total parenteral nutrition after major pancreatic resection for malignancy
Conference Title: 114th Annual Scientific Session of the American Surgical Association
Abstract: Objectives: The authors examined the impact of adjuvant total parenteral nutrition after major pancreatic resection for malignancy. Summary Background Data: Previous studies have suggested a benefit to perioperative nutritional support for patients undergoing major gastrointestinal surgery. Methods: A prospective, randomized study was conducted using patients who had undergone a major pancreatic resection with randomization on postoperative day one to either receive or not receive adjuvant total parenteral nutrition. Results: No benefit could be demonstrated by the use of adjuvant parenteral nutrition in this setting. Complications were significantly greater in the group receiving total parenteral nutrition. These complications tended to be those associated with infection. Conclusions: Routine applications of postoperative parenteral nutrition to patients undergoing major pancreatic resection for malignancy cannot be recommended. Further studies are required to determine the reason that infectious complications in these patients are increased.
Keywords: adult; controlled study; aged; major clinical study; clinical trial; fistula; conference paper; pancreas cancer; pancreas resection; controlled clinical trial; infection; reoperation; total parenteral nutrition; intestine obstruction; abscess; nutritional support; human; male; female; priority journal
Journal Title Annals of Surgery
Volume: 220
Issue: 4
Conference Dates: 1994 Apr 7-9
Conference Location: San Antonio, TX
ISBN: 0003-4932
Publisher: Lippincott Williams & Wilkins  
Date Published: 1994-10-01
Start Page: 436
End Page: 441; discussion 441-444
Language: English
DOI: 10.1097/00000658-199410000-00003
PUBMED: 7944656
PROVIDER: scopus
PMCID: PMC1234412
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027959890&doi=10.1097%2f00000658-199410000-00003&partnerID=40&md5=da5b5d7a8cd229b9702eff834661e6b5
Notes: Source: Scopus
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MSK Authors
  1. Murray F Brennan
    1059 Brennan
  2. Moshe Shike
    168 Shike
  3. Ofelia C Quesada
    4 Quesada
  4. Peter W. T. Pisters
    21 Pisters
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