Authors: | Holland, A. M.; Zakrzewski, J. L.; Goldberg, G. L.; Ghosh, A.; van den Brink, M. R. M. |
Article Title: | Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man |
Abstract: | Hematopoietic stem cell transplantation is a curative therapy for hematological malignancies. T cell deficiency following transplantation is a major cause of morbidity and mortality. In this review, we discuss adoptive transfer of committed precursor cells to enhance T cell reconstitution and improve overall prognosis after transplantation. © 2008 Springer-Verlag. |
Keywords: | mortality; review; nonhuman; t lymphocyte; t-lymphocytes; animals; mice; cell maturation; dendritic cell; morbidity; notch receptor; hematopoietic stem cell transplantation; b lymphocyte; pre t lymphocyte; cell isolation; hematopoietic stem cell; major histocompatibility complex; bone marrow transplantation; thymocyte; adoptive immunotherapy; immunotherapy, adoptive; natural killer t cell; immune reconstitution; t cell |
Journal Title: | Seminars in Immunopathology |
Volume: | 30 |
Issue: | 4 |
ISSN: | 1863-2297 |
Publisher: | Springer |
Date Published: | 2008-01-01 |
Start Page: | 479 |
End Page: | 487 |
Language: | English |
DOI: | 10.1007/s00281-008-0138-z |
PUBMED: | 19015856 |
PROVIDER: | scopus |
PMCID: | PMC4806790 |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "Source: Scopus" |