Hepatocellular carcinoma mimicking neuroendocrine tumor metastasis on (68)Ga-DOTATATE PET/CT Miscellaneous

   


Authors: Ulaner, G. A.; Bodei, L.
Title: Hepatocellular carcinoma mimicking neuroendocrine tumor metastasis on (68)Ga-DOTATATE PET/CT
Abstract: 68 Ga-DOTATATE is a radiolabeled somatostatin analog used for the detection and characterization of somatostatin receptor (SSR)-overexpressing tumors, particularly well-differentiated neuroendocrine tumors. We present a case of a 65-year-old man with well-differentiated pancreatic neuroendocrine tumor post-Whipple surgery and a new liver lesion on CT. 68 Ga-DOTATATE PET/CT was performed for SSR characterization and restaging, which demonstrated the lesion to be intensely SSR positive and interpreted as a neuroendocrine metastasis. However, subsequent pathology proved the lesion to be a hepatocellular carcinoma. This case adds hepatocellular carcinoma as a potentially DOTATATE-avid malignancy to be considered in the differential diagnoses of SSR-positive liver lesions. © 2018 Wolters Kluwer Health, Inc. All rights reserved.
Keywords: hepatocellular carcinoma; dotatate; somatostatin receptors; 68 ga; netspot
Journal Title: Clinical Nuclear Medicine
Volume: 44
Issue: 4
ISSN: 0363-9762
Publisher: Lippincott Williams & Wilkins  
Date Published: 2019-04-01
Start Page: 330
End Page: 331
Language: English
DOI: 10.1097/rlu.0000000000002467
PUBMED: 30688738
PROVIDER: scopus
PMCID: PMC6687392
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062408390&doi=10.1097%2fRLU.0000000000002467&partnerID=40&md5=50ca782e17e5ccff198b6e64c226736e
Notes: Source: Scopus
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MSK Authors
  1. Gary Ulaner
    147 Ulaner
  2. Lisa Bodei
    210 Bodei
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