Chromosomal localization of genes encoding the transcription factors, c-rel, NF-κBp50, NF-κBp65, and lyt-10 by fluorescence in situ hybridization Journal Article
| Authors: | Mathew, S.; Murty, V. V. V. S.; Dalla-Favera, R.; Chaganti, R. S. K. |
| Article Title: | Chromosomal localization of genes encoding the transcription factors, c-rel, NF-κBp50, NF-κBp65, and lyt-10 by fluorescence in situ hybridization |
| Abstract: | We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-κcBp50, NF-κBp65, and lyt-10. The previously published assignments of c-rel and NF-κcBp50 have been refined to specific bands. The map position of lyt-10, inferred from its isolation from a t(10;14)(q24;q32) translocation, has been confirmed. NF-κBp65 has now been mapped to 11q13, a site of frequent involvement in aberration in multiple tumor types. |
| Keywords: | proto-oncogene proteins; gene; fluorescence; transcription factor; transcription factors; in situ hybridization; gene mapping; fluorescence in situ hybridization; nf-kappa b; chromosome 11q; chromosomal localization; chromosome mapping; proto-oncogene proteins c-rel; chromosome band; human; priority journal; article; support, u.s. gov't, p.h.s.; gene assignment |
| Journal Title: | Oncogene |
| Volume: | 8 |
| Issue: | 1 |
| ISSN: | 0950-9232 |
| Publisher: | Nature Publishing Group |
| Date Published: | 1993-01-01 |
| Start Page: | 191 |
| End Page: | 193 |
| Language: | English |
| PUBMED: | 8423996 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 March 2019 -- Source: Scopus |
Citation Impact
Related MSK Work