Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein Journal Article


Authors: Andrews, N. C.; Erdjument-Bromage, H.; Davidson, M. B.; Tempst, P.; Orkin, S. H.
Article Title: Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein
Abstract: Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2. © 1993 Nature Publishing Group.
Keywords: mutation; dna-binding proteins; nonhuman; animal cell; mouse; animal; mice; gene expression; cell line; transcription factor; tumor cells, cultured; transfection; animalia; transcription factors; cloning, molecular; dna; amino acid sequence; molecular sequence data; peptides; erythroid cell; globin gene; base sequence; hematopoiesis; binding sites; erythrocytes; protein dna interaction; globins; tissue specificity; zinc fingers; consensus sequence; leucine zipper protein; leukemia, erythroblastic, acute; priority journal; article; leucine zippers; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
Journal Title: Nature
Volume: 362
Issue: 6422
ISSN: 0028-0836
Publisher: Nature Publishing Group  
Date Published: 1993-04-22
Start Page: 722
End Page: 728
Language: English
DOI: 10.1038/362722a0
PUBMED: 8469283
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 March 2019 -- Source: Scopus
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  1. Paul J Tempst
    324 Tempst