Authors: | Andrews, N. C.; Erdjument-Bromage, H.; Davidson, M. B.; Tempst, P.; Orkin, S. H. |
Article Title: | Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein |
Abstract: | Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2. © 1993 Nature Publishing Group. |
Keywords: | mutation; dna-binding proteins; nonhuman; animal cell; mouse; animal; mice; gene expression; cell line; transcription factor; tumor cells, cultured; transfection; animalia; transcription factors; cloning, molecular; dna; amino acid sequence; molecular sequence data; peptides; erythroid cell; globin gene; base sequence; hematopoiesis; binding sites; erythrocytes; protein dna interaction; globins; tissue specificity; zinc fingers; consensus sequence; leucine zipper protein; leukemia, erythroblastic, acute; priority journal; article; leucine zippers; support, non-u.s. gov't; support, u.s. gov't, p.h.s. |
Journal Title: | Nature |
Volume: | 362 |
Issue: | 6422 |
ISSN: | 0028-0836 |
Publisher: | Nature Publishing Group |
Date Published: | 1993-04-22 |
Start Page: | 722 |
End Page: | 728 |
Language: | English |
DOI: | 10.1038/362722a0 |
PUBMED: | 8469283 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 1 March 2019 -- Source: Scopus |