Drug therapy for neuropathic pain Journal Article


Author: Portenoy, R. K.
Article Title: Drug therapy for neuropathic pain
Abstract: Optimal therapy for neuropathic pain requires ongoing assessment and multiple treatment modalities, including pharmacotherapy. Pharmacologic interventions encompass traditional analgesic agents as well as a variety of agents with analgesic potential for certain types of pain or for specific patient subpopulations. Drug trials must be managed by a practitioner who has primary responsibility for titration, ongoing assessment, and monitoring for side effects and adverse reactions. The success of therapy is measured by pain relief and functional improvement.
Keywords: patient selection; side effect; pain; neuropathy; opiate; sedation; inflammation; patient education; drug screening; hypotension; nonsteroid antiinflammatory agent; antidepressant agent; benzodiazepine derivative; neuroleptic agent; anticonvulsive agent; corticosteroid; alprazolam; calcium channel blocking agent; clonazepam; fluoxetine; levomepromazine; phenytoin; analgesic agent; mexiletine; pimozide; local anesthetic agent; oral drug administration; tricyclic antidepressant agent; muscle relaxant agent; capsaicin; clonidine; phenoxybenzamine; clomipramine; nortriptyline; adrenergic receptor blocking agent; baclofen; human; article; transdermal drug administration; tocainide
Journal Title: Drug Therapy
Volume: 23
Issue: 1
ISSN: 0001-7094
Publisher: Excerpta Medica * Core Medical Journals  
Date Published: 1993-01-01
Start Page: 41
End Page: 44, 51-53
Language: English
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus