The origin of mediastinal germ cell tumors in men Journal Article


Authors: Rosai, J.; Parkash, V.; Reuter, V. E.
Article Title: The origin of mediastinal germ cell tumors in men
Abstract: Mediastinal germ-cell tumors in men are generally thought to be primary at this site and to arise from extragonadal germ cells located in the thymus gland. Recent cytoge netic data have cast some doubt on this hypothesis and revived the alternative possibil ity of a testicular origin for these lesions. However, a review of the available evidence suggests that a primary mediastinal origin still remains the most likely explanation. The suggestion is made that the difficulties in identifying normal germ cells in the thymus gland may be due to their evolving into some type of somatic cell such as a myoid cell. Int J Surg Pathol 2(1):73-78, 1994 © 1994, Sage Publications. All rights reserved.
Keywords: germ cells; thymus; mediastinum; germ-cell tumors; pineal; myoid cells
Journal Title: International Journal of Surgical Pathology
Volume: 2
Issue: 1
ISSN: 1066-8969
Publisher: Sage Publications  
Date Published: 1994-07-01
Start Page: 73
End Page: 78
Language: English
DOI: 10.1177/106689699400200112
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 February 2019 -- Source: Scopus
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  1. Juan Rosai
    181 Rosai
  2. Victor Reuter
    1228 Reuter