Methods for the study of entotic cell death Journal Article


Authors: Hamann, J. C.; Kim, S. E.; Overholtzer, M.
Article Title: Methods for the study of entotic cell death
Abstract: Entosis is a mechanism of cell competition occurring in cancers that involves the engulfment and killing of neighboring cells. The death of ingested cells, called entotic cell death, usually occurs in a non-apoptotic, autophagy protein-dependent manner, where microtubule-associated protein light chain 3 (LC3) is lipidated onto entotic vacuoles. Here we present methods to quantify entotic cell death and its associated LC3 lipidation. © Springer Science+Business Media, LLC, part of Springer Nature 2019.
Keywords: time-lapse; entosis; cannibalism; engulfment; anoikis; cell-in-cell; soft agar
Journal Title: Methods in Molecular Biology
Volume: 1880
ISSN: 1064-3745
Publisher: Humana Press Inc  
Date Published: 2019-01-01
Start Page: 447
End Page: 454
Language: English
DOI: 10.1007/978-1-4939-8873-0_28
PUBMED: 30610714
PROVIDER: scopus
DOI/URL:
Notes: Book Chapter 28 in "Autophagy: Methods and Protocols" (ISBN: 978-1-4939-8872-3) -- Export Date: 1 February 2019 -- Source: Scopus
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MSK Authors
  1. Jens C Hamann
    7 Hamann
  2. Sung Eun Kim
    6 Kim