Non-Hodgkin lymphoma of the breast: Imaging characteristics and correlation with histopathologic findings Journal Article


Authors: Liberman, L.; Giess, C. S.; Dershaw, D. D.; Louie, D. C.; Deutch, B. M.
Article Title: Non-Hodgkin lymphoma of the breast: Imaging characteristics and correlation with histopathologic findings
Abstract: PURPOSE: To determine the imaging characteristics of non-Hodgkin lymphoma (NHL) of the breast and correlate these findings with histopathologic subtype. MATERIALS AND METHODS: The authors retrospectively reviewed records in 32 cases of histologically proved NHL in 29 women. Mammography was performed before biopsy in all cases, and breast sonography was performed before biopsy in eight. RESULTS: Mammary NHL was primary in 21 of the 32 cases (66%) and secondary in 11 (34%). Mammography revealed a solitary, uncalcified mass in 22 cases (69%), multiple masses in three (9%), and diffuse increased opacity with skin thickening in three (9%). Four cases (13%) had normal findings. Seven of the eight sonograms revealed masses, which were solitary in five and multiple in two. Histologic examination showed diffuse NHL in 26 cases (81%) and follicular NHL in six (19%). No mammographic or sonographic features were identified that helped distinguish primary from secondary disease or follicular from diffuse NHL CONCLUSION: Although the imaging characteristics may suggest the possibility of breast NHL, none of the findings are pathognomonic. The imaging pattern of mammary NHL is unrelated to its histopathologic subtype.
Keywords: adult; clinical article; aged; histopathology; preoperative evaluation; diagnostic imaging; breast neoplasms; nonhodgkin lymphoma; mammography; breast tumor; echography; tumor diagnosis; breast biopsy; human; female; priority journal; article; lymphoma, diagnosis
Journal Title: Radiology
Volume: 192
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1994-07-01
Start Page: 157
End Page: 160
Language: English
DOI: 10.1148/radiology.192.1.8208929
PROVIDER: scopus
PUBMED: 8208929
DOI/URL:
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MSK Authors
  1. D David Dershaw
    223 Dershaw
  2. Laura Liberman
    176 Liberman
  3. Diane C Louie
    52 Louie
  4. Beth M. Deutch
    10 Deutch