Imaging of pregnancy-associated breast cancer Journal Article
| Authors: | Liberman, L.; Giess, C. S.; Dershaw, D. D.; Deutch, B. M.; Petrek, J. A. |
| Article Title: | Imaging of pregnancy-associated breast cancer |
| Abstract: | PURPOSE: To assess the use of mammography in diagnosis of pregnancy- associated breast cancer (PABC). MATERIALS AND METHODS: A retrospective review of medical records between 1973 and 1993 was performed in 85 women with breast cancer diagnosed during pregnancy or within 1 year after pregnancy. In 21 of these women, mammography was performed before biopsy; the mammographic findings in this study group, which had 23 cases of invasive carcinoma, were reviewed for signs of malignancy. Breast sonography was performed in six cases in five women; sonographic findings were also reviewed. RESULTS: Mammographic findings were present in 18 of 23 cases (78%), including mass (n = 13) (nine cases with calcification), suspicious calcifications (n = 4), and diffusely increased parenchymal density (n = 1). Breast sonography revealed focal solid mass in six of six cases. Axillary lymph node metastases occurred in 15 of 23 cases (65%). Although symptoms occurred before or during pregnancy in 12 cases (52%), PABC was diagnosed after pregnancy in 19 cases (83%). CONCLUSION: PABC is often advanced at diagnosis and associated with poor prognosis. Breast imaging studies usually demonstrate focal findings due to clinically evident PABC. |
| Keywords: | adult; clinical article; human tissue; lymph node metastasis; breast cancer; echomammography; axillary lymph node; diagnostic value; breast tumor; pregnancy; invasive carcinoma; breast biopsy; breast calcification; pregnancy complication; human; female; priority journal; article; breast neoplasms, diagnosis; breast radiography, utilization |
| Journal Title: | Radiology |
| Volume: | 191 |
| Issue: | 1 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 1994-04-01 |
| Start Page: | 245 |
| End Page: | 248 |
| Language: | English |
| DOI: | 10.1148/radiology.191.1.8134581 |
| PROVIDER: | scopus |
| PUBMED: | 8134581 |
| DOI/URL: |
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