Lung transplantation for chemotherapy-induced pulmonary fibrosis Journal Article


Authors: Santamauro, J. T.; Stover, D. E.; Jules-Elysee, K.; Maurer, J. R.
Article Title: Lung transplantation for chemotherapy-induced pulmonary fibrosis
Abstract: A 26-year-old man cured of childhood acute lymphoblastic leukemia underwent a single lung transplant for drug-induced pulmonary toxicity 9 years after the completion of chemotherapy. It is not known whether patients cured of a malignancy who undergo organ transplantation are at increased risk of malignancy as compared to other organ transplant recipients. There was no evidence of recurrent or secondary malignancy in this case. Since single lung transplantation has been effective for idiopathic pulmonary fibrosis, it should be considered for patients cured of a malignancy who develop chemotherapy-induced pulmonary fibrosis.
Keywords: adult; case report; cancer combination chemotherapy; cytarabine; methotrexate; lung toxicity; cyclophosphamide; vincristine; carmustine; chlormethine; acute lymphoblastic leukemia; childhood cancer; daunorubicin; dactinomycin; asparaginase; lung fibrosis; tioguanine; mercaptopurine; respiratory failure; oral drug administration; lung transplantation; hemoptysis; fatality; human; male; priority journal; article; intrathecal drug administration
Journal Title: Chest
Volume: 105
Issue: 1
ISSN: 0012-3692
Publisher: American College of Chest Physicians  
Date Published: 1994-01-01
Start Page: 310
End Page: 312
Language: English
DOI: 10.1378/chest.105.1.310
PROVIDER: scopus
PUBMED: 8275763
DOI/URL:
Notes: Export Date: 14 January 2019 -- Article -- Source: Scopus
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