Major changes in head and neck staging for 2018 Journal Article


Authors: Lydiatt, W.; O'Sullivan, B.; Patel, S.
Article Title: Major changes in head and neck staging for 2018
Abstract: Oncologists should be aware of three major modifications and additions to staging head and neck cancer that became effective in 2018. Oral cavity cancers have the addition of depth of invasion; oropharyngeal cancers (OPCs) are now distinguished by the immunohistochemical stain, p16, into those that are associated with high-risk human papillomavirus and those that are not; and all sites except nasopharyngeal carcinoma and high-risk human papillomavirus OPC will now include the important parameter of extranodal extension. The rationale and emerging data supporting these changes are discussed in this article and the accompanying oral presentation at the 2018 ASCO Annual Meeting.
Keywords: mortality; cancer staging; neoplasm staging; tumor volume; practice guideline; biopsy; virology; head and neck neoplasms; tumor burden; practice guidelines as topic; neoplasm invasiveness; disease management; head and neck tumor; papillomavirus infections; complication; papillomavirus infection; tumor invasion; procedures; humans; prognosis; human
Journal Title: American Society of Clinical Oncology Educational Book
Volume: 38
ISSN: 1548-8756
Publisher: American Society of Clinical Oncology  
Date Published: 2018-05-23
Start Page: 505
End Page: 514
Language: English
DOI: 10.1200/edbk_199697
PROVIDER: scopus
PUBMED: 30231400
DOI/URL:
Notes: Am Soc Clin Oncol Educ Book -- Export Date: 2 January 2019 -- Review -- Source: Scopus C2 - 30231400
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  1. Snehal G Patel
    412 Patel