Surgery for early-stage small cell lung cancer Journal Article
| Authors: | Schneider, B. J.; Saxena, A.; Downey, R. J. |
| Article Title: | Surgery for early-stage small cell lung cancer |
| Abstract: | Limited-stage small cell lung cancer remains one of the more frustrating malignancies to treat. Current standard of care typically includes platinum-based chemotherapy with thoracic radiation, and although response to therapy is high, most patients will ultimately experience relapse and die of recurrent disease. No high-level data exist supporting surgical resection of early-stage disease; however, several retrospective reviews and small single-arm studies suggest surgery may benefit patients with very limited extent of disease. This article reviews the available literature, and proposes guidelines for including potentially curative resection in the management of patients with limited-stage small cell lung cancer. © JNCCN-Journal of the National Comprehensive Cancer Network. |
| Keywords: | cancer chemotherapy; treatment outcome; cancer surgery; overall survival; histopathology; review; clinical trials as topic; cancer radiotherapy; combined modality therapy; cancer staging; antineoplastic agent; neoplasm staging; lung neoplasms; practice guideline; data base; lung small cell cancer; surgery; mixed tumor; resection; chemoradiotherapy; small cell lung cancer; small cell lung carcinoma; multimodality therapy; randomized controlled trial (topic); phase 2 clinical trial (topic) |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 9 |
| Issue: | 10 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2011-10-01 |
| Start Page: | 1132 |
| End Page: | 1139 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 21975913 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 November 2011" - "Source: Scopus" |
