How I treat breast implant-associated anaplastic large cell lymphoma Journal Article


Authors: Mehta-Shah, N.; Clemens, M. W.; Horwitz, S. M.
Article Title: How I treat breast implant-associated anaplastic large cell lymphoma
Abstract: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a recently described form of T-cell non-Hodgkin lymphoma now formally recognized by the World Health Organization classification of lymphoid neoplasms. The disease most often presents with a delayed seroma around the breast implant, almost exclusively with a textured surface, and manifests with breast pain, swelling or asymmetry, capsular contracture, but can also present with a breast mass, and lymph node involvement. The prognosis of BIA-ALCL is favorable compared with many other subtypes of systemic T-cell lymphoma; however, unlike other non-Hodgkin lymphomas, complete surgical excision for localized disease is an important part of the management of these patients. In this paper, we share our recommendations for a multidisciplinary team approach to the diagnosis, workup, and treatment of BIA-ALCL in line with consensus guidelines by the National Comprehensive Cancer Network. © 2018 by The American Society of Hematology.
Journal Title: Blood
Volume: 132
Issue: 18
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2018-11-01
Start Page: 1889
End Page: 1898
Language: English
DOI: 10.1182/blood-2018-03-785972
PUBMED: 30209119
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 3 December 2018 -- Source: Scopus
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  1. Steven M Horwitz
    338 Horwitz