Clinical potential of human epidermal growth factor receptor 2 and human epidermal growth factor receptor 3 imaging in breast cancer Journal Article

   


Authors: Henry, K. E.; Ulaner, G. A.; Lewis, J. S.
Article Title: Clinical potential of human epidermal growth factor receptor 2 and human epidermal growth factor receptor 3 imaging in breast cancer
Abstract: Increased expression of the human epidermal growth factor receptor (HER) protein family are targets in breast cancer for imaging and therapy. Imaging modalities targeting HER2 and HER3 can diagnose breast cancer with a specific, biologically relevant target. Repeat biopsies do not address heterogeneity intratumorally or between primary disease and metastasis. HER2- and HER3-targeted PET is an important tool to diagnose disease in breast cancer and evaluate response to targeted therapies. PET and single photon emission computed tomography with radiolabeled biomolecules can be used to detect and quantify specific targets, conferring a better understanding of the behavior and effectiveness of treatments. © 2018 Elsevier Inc.
Keywords: metastasis; breast cancer; pet; ct; her2; spect; radiotracers; her3
Journal Title: PET Clinics
Volume: 13
Issue: 3
ISSN: 1556-8598
Publisher: Elsevier Inc.  
Date Published: 2018-07-01
Start Page: 423
End Page: 435
Language: English
DOI: 10.1016/j.cpet.2018.02.010
PROVIDER: scopus
PMCID: PMC6092024
PUBMED: 30100080
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049344324&doi=10.1016%2fj.cpet.2018.02.010&partnerID=40&md5=aaaecd73c9c24871cfaa43de4da7900a
Notes: Review -- Export Date: 1 August 2018 -- Source: Scopus
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MSK Authors
  1. Gary Ulaner
    146 Ulaner
  2. Jason S Lewis
    456 Lewis
  3. Kelly Elizabeth Henry
    17 Henry
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