Determination of the fate and function of innate lymphoid cells following adoptive transfer of innate lymphoid cell precursors Journal Article
| Authors: | O’Sullivan, T. E.; Sun, J. C. |
| Article Title: | Determination of the fate and function of innate lymphoid cells following adoptive transfer of innate lymphoid cell precursors |
| Abstract: | Innate lymphoid cells are a heterogeneous family of tissue-resident and circulating lymphocytes that play an important role in host immunity. Recent studies have profiled the developmental pathways of mature ILCs and have identified ILC progenitors in the bone marrow through the use of transcription factor reporter mice. Here we describe methodology to identify and isolate bone marrow CHILP and ILC2 progenitor (ILC2P) cells based on cell surface marker expression for adoptive transfer into lymphopenic mice to track the fate of developing ILCs. © 2018, Springer Science+Business Media, LLC, part of Springer Nature. |
| Keywords: | adoptive transfer; precursors; innate lymphoid cells |
| Journal Title: | Methods in Molecular Biology |
| Volume: | 1799 |
| ISSN: | 1064-3745 |
| Publisher: | Humana Press Inc |
| Date Published: | 2018-01-01 |
| Start Page: | 109 |
| End Page: | 119 |
| Language: | English |
| DOI: | 10.1007/978-1-4939-7896-0_10 |
| PROVIDER: | scopus |
| PUBMED: | 29956148 |
| DOI/URL: | |
| Notes: | Book Chapter 10 in "Type 2 Immunity: Methods and Protocols" (ISBN: 978-1-4939-7895-3)-- Export Date: 1 August 2018 -- Source: Scopus |
