Resistance of nonmelanoma skin cancer to nonsurgical treatments. Part I: Topical treatments Journal Article
| Authors: | Gracia-Cazaña, T.; González, S.; Gilaberte, Y. |
| Article Title: | Resistance of nonmelanoma skin cancer to nonsurgical treatments. Part I: Topical treatments |
| Abstract: | A wide range of treatments is now available for nonmelanoma skin cancer (NMSC), including 5-fluorouracil, ingenol mebutate, imiquimod, diclofenac, photodynamic therapy, methotrexate, cetuximab, vismodegib, and radiotherapy. All are associated with high clinical and histologic response rates. However, some tumors do not respond due to resistance, which may be primary or acquired. Study of the resistance processes is a broad area of research that aims to increase our understanding of the nature of each tumor and the biologic features that make it resistant, as well as to facilitate the design of new therapies directed against these tumors. In this article we review resistance to the authorized topical treatments for NMSC. © 2016 Elsevier España, S.L.U. and AEDV |
| Keywords: | imiquimod; skin cancer; diclofenac; 5-fluorouracil; ingenol |
| Journal Title: | Actas Dermo-Sifiliográficas |
| Volume: | 107 |
| Issue: | 9 |
| ISSN: | 0001-7310 |
| Publisher: | Elsevier España |
| Date Published: | 2016-11-01 |
| Start Page: | 730 |
| End Page: | 739 |
| Language: | English; Spanish |
| DOI: | 10.1016/j.adengl.2016.08.016 |
| PROVIDER: | scopus |
| PUBMED: | 27436800 |
| DOI/URL: | |
| Notes: | Resistencias al tratamiento no quirúrgico en cáncer cutáneo no melanoma. Parte I: tratamientos tópicos -- For a Spanish language version see: 10.1016/j.ad.2016.04.019 -- Short Survey -- Export Date: 1 May 2018 -- Source: Scopus |
