Authors: | Miller, S. J.; Alam, M.; Andersen, J.; Berg, D.; Bichakjian, C. K.; Bowen, G.; Cheney, R. T.; Glass, L. F.; Grekin, R. C.; Kessinger, A.; Lee, N. Y.; Liegeois, N.; Lydiatt, D. D.; Michalski, J.; Morrison, W. H.; Nehal, K. S.; Nelson, K. C.; Nghiem, P.; Olencki, T.; Perlis, C. S.; Rosenberg, E. W.; Shaha, A. R.; Urist, M. M.; Wang, L. C.; Zic, J. A. |
Article Title: | Basal cell and squamous cell skin cancers |
Abstract: | Basal and squamous cell skin cancers, collectively known as nonmelanoma skin cancers (NMSC), are the most common skin cancers. More than 1 million cases of NMSC are estimated to be diagnosed each year in the United States, and the incidence is rising rapidly. Although rarely metastatic, basal and squamous cell cancers can produce substantial local destruction, along with disfigurement. They are associated with substantial annual costs for treatment, despite their general good prognosis. The most significant environmental carcinogen for NMSC is sunlight. Most of these tumors develop on sun-exposed skin sites, commonly on the head and neck area. Important updates for 2010 include revision of the guidelines detailing dissection and treatment of squamous cell carcinoma on the head and neck. © Journal of the National Comprehensive Cancer Network. |
Keywords: | cancer survival; cancer surgery; excision; clinical feature; clinical trial; histopathology; review; cancer localization; cancer recurrence; intensity modulated radiation therapy; squamous cell carcinoma; carcinoma, squamous cell; cisplatin; doxorubicin; fluorouracil; cancer combination chemotherapy; cancer growth; cancer risk; drug dose reduction; united states; alpha interferon; paclitaxel; adjuvant therapy; cancer adjuvant therapy; cancer patient; cancer radiotherapy; recurrence risk; follow up; lymph node metastasis; cancer diagnosis; cancer incidence; lymph node dissection; cancer palliative therapy; cancer prevention; imiquimod; actinic keratosis; basal cell carcinoma; skin biopsy; sun exposure; skin neoplasms; tumor differentiation; risk factors; patient education; nccn clinical practice guidelines; cyclophosphamide; clinical protocol; skin carcinoma; vinblastine; patient identification; radiation exposure; age; cancer survivor; health care cost; medicare; cancer genetics; radiation dose fractionation; skin examination; cancer size; bleomycin; high risk population; graft rejection; isotretinoin; mammalian target of rapamycin inhibitor; immunosuppressive treatment; calcineurin inhibitor; ultraviolet a radiation; parameter; awareness; frozen section; photodynamic therapy; neurologic disease; carcinoma, basal cell; chemosurgery; retinoic acid; sunlight; graft recipient; retinoid; ablation therapy; antimetabolite; cryosurgery; immunosuppressive agent; curettage; cryotherapy; photofrin; nccn guidelines; aminolevulinic acid; bowen disease; teratogenicity; skin protection; partial body radiation; cheilitis; basosquamous carcinoma; bowen's disease; non-melanoma skin cancers; precancerous lesions; sunlight and cancer; aminolevulinic acid methyl ester; etretin; electrodesiccation; organ transplantation; skin color |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 8 |
Issue: | 8 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2010-08-01 |
Start Page: | 836 |
End Page: | 864 |
Language: | English |
PUBMED: | 20870631 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 20 April 2011" - "Source: Scopus" |