Abstract: |
Functional MRI and diffusion tensor imaging (DTI) have been used in the treatment of gliomas for over two decades. Their development as practical clinical tools has been driven by advancements in professional training as much as in technique and methods. How these advanced imaging results are incorporated into clinical decision making requires careful consideration. Neither fMRI nor DTI measures function or connectivity directly, but rather both use physiological properties of blood oxygenation and water diffusion, respectively, as a proxy measure from which predictive models are derived. As such, output can be heavily dependent on many design and technical factors. In most cases, advanced neuroimaging serves to compliment invasive direct cortical stimulation in that it can guide intraoperative mapping or add information about whether an awake neurosurgical procedure is necessary. What follows is a discussion of the strengths and weaknesses of both techniques in the treatment of gliomas. © Springer International Publishing AG 2017. |