Use of advanced neuroimaging (fMRI, DTI/Tractography) in the treatment of malignant gliomas Book Section


Authors: Petrovich Brennan, N. M.; Holodny, A. I.
Editors: Günel, J. M.; Piepmeier, J. M.; Baehring, J. M.
Article/Chapter Title: Use of advanced neuroimaging (fMRI, DTI/Tractography) in the treatment of malignant gliomas
Abstract: Functional MRI and diffusion tensor imaging (DTI) have been used in the treatment of gliomas for over two decades. Their development as practical clinical tools has been driven by advancements in professional training as much as in technique and methods. How these advanced imaging results are incorporated into clinical decision making requires careful consideration. Neither fMRI nor DTI measures function or connectivity directly, but rather both use physiological properties of blood oxygenation and water diffusion, respectively, as a proxy measure from which predictive models are derived. As such, output can be heavily dependent on many design and technical factors. In most cases, advanced neuroimaging serves to compliment invasive direct cortical stimulation in that it can guide intraoperative mapping or add information about whether an awake neurosurgical procedure is necessary. What follows is a discussion of the strengths and weaknesses of both techniques in the treatment of gliomas. © Springer International Publishing AG 2017.
Keywords: functional mri; diffusion tractography; resting state functional mri; advanced neuroimaging; glioma mapping
Book Title: Malignant Brain Tumors: State-of-the-Art Treatment
ISBN: 978-3-319-49863-8
Publisher: Springer International Publishing  
Publication Place: Cham, Switzerland
Date Published: 2017-01-01
Start Page: 3
End Page: 13
Language: English
DOI: 10.1007/978-3-319-49864-5_1
PROVIDER: scopus
DOI/URL:
Notes: Book Chapter: 1 -- Export Date: 2 April 2018 -- Source: Scopus
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MSK Authors
  1. Nicole Brennan
    41 Brennan
  2. Andrei Holodny
    136 Holodny