The role of advanced imaging in spinal metastases Book Section


Authors: Karimi, S.; Cho, N. S.; Peck, K. K.; Holodny, A. I.
Editors: Ramakrishna, R.; Magge, R. S.; Baaj, A. A.; Knisely, J. P. S.
Article/Chapter Title: The role of advanced imaging in spinal metastases
Abstract: Accurate diagnosis and assessment of spinal metastases are of critical importance for cancer patients because the spine is the most common site for skeletal metastases. Conventional imaging methods such as bone scan, positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT) are commonly utilized for diagnosing and monitoring treatment of spinal metastases. However, differential diagnoses and treatment response monitoring currently remain difficult with these methods. The development of advanced imaging techniques offers promising advantages to conventional methods through considerations of diffusion, perfusion, and other tumor microenvironment characteristics. These advanced imaging techniques include dynamic contrast-enhanced MRI (DCE MRI), which shows great potential for improving the management of spinal metastases by assessing tumor vascularity, as well as diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), dual-energy CT, and CT myelography. This chapter will discuss how these techniques can be specifically utilized throughout a patient’s treatment timeline to enhance clinical care. © Springer Nature Switzerland AG 2020.
Keywords: treatment response; magnetic resonance imaging; diagnosis; chordoma; dynamic contrast-enhanced mri; spinal cord injury; computed tomography; fractures; diffusion tensor imaging; diffusion-weighted imaging; perfusion mri; conventional imaging; spine metastases; dual-energy ct; ct myelography; hypervascular metastases; hypovascular metastases
Book Title: Central Nervous System Metastases: Diagnosis and Treatment
ISBN: 978-3-030-42957-7
Publisher: Springer  
Publication Place: Cham, Switzerland
Date Published: 2020-01-01
Start Page: 523
End Page: 534
Language: English
DOI: 10.1007/978-3-030-42958-4_38
PROVIDER: scopus
DOI/URL:
Notes: Book chapter: 38 -- This chapter can be found under "Part V Spinal Metastases: Foundations" -- Source: Scopus
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  1. Sasan Karimi
    114 Karimi
  2. Kyung Peck
    116 Peck
  3. Andrei Holodny
    206 Holodny
  4. Nicholas Cho
    5 Cho