Silencing stemness in T cell differentiation: Epigenetic repression is required for the generation of CD8(+) effector T cells Journal Article
| Authors: | Henning, A. N.; Klebanoff, C. A.; Restifo, N. P. |
| Article Title: | Silencing stemness in T cell differentiation: Epigenetic repression is required for the generation of CD8(+) effector T cells |
| Keywords: | genetics; review; nonhuman; genetic analysis; cd8+ t lymphocyte; cell proliferation; t lymphocyte; cancer immunotherapy; apoptosis; immune system; gene expression; cell infiltration; protein; developmental biology; cell differentiation; antineoplastic activity; cell population; dna methylation; cell lineage; stem cell; lymphocyte differentiation; dna; immune response; neoplastic stem cells; epigenetics; cancer stem cell; effector cell; immunoassay; gene silencing; adaptive immunity; memory cell; t lymphocyte activation; memory t lymphocyte; dna methyltransferase 3a; cell; transcription factor ezh2; cell dedifferentiation; cell self-renewal; cancer; humans; human; priority journal |
| Journal Title: | Science |
| Volume: | 359 |
| Issue: | 6372 |
| ISSN: | 0036-8075 |
| Publisher: | American Association for the Advancement of Science |
| Date Published: | 2018-01-12 |
| Start Page: | 163 |
| End Page: | 164 |
| Language: | English |
| DOI: | 10.1126/science.aar5541 |
| PUBMED: | 29326263 |
| PROVIDER: | scopus |
| PMCID: | PMC6312704 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 February 2018 -- Source: Scopus |
