Pluripotent stem cells in neuropsychiatric disorders Journal Article

   


Authors: Soliman, M. A.; Aboharb, F.; Zeltner, N.; Studer, L.
Article Title: Pluripotent stem cells in neuropsychiatric disorders
Abstract: Neuropsychiatric disorders place an enormous medical burden on patients across all social and economic ranks. The current understanding of the molecular and cellular causes of neuropsychiatric disease remains limited, which leads to a lack of targeted therapies. Human-induced pluripotent stem cell (iPSC) technology offers a novel platform for modeling the genetic contribution to mental disorders and yields access to patient-specific cells for drug discovery and personalized medicine. Here, we review recent progress in using iPSC technology to model and potentially treat neuropsychiatric disorders by focusing on the most prevalent conditions in psychiatry, including depression, anxiety disorders, bipolar disorder and schizophrenia. © The Author(s) 2017.
Journal Title: Molecular Psychiatry
Volume: 22
Issue: 9
ISSN: 1359-4184
Publisher: Nature Publishing Group  
Date Published: 2017-09-01
Start Page: 1241
End Page: 1249
Language: English
DOI: 10.1038/mp.2017.40
PROVIDER: scopus
PUBMED: 28322279
PMCID: PMC5582162
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85015703533&doi=10.1038%2fmp.2017.40&partnerID=40&md5=85615cd92b163e9bce8f519ae54d7b77
Notes: Review -- Export Date: 1 September 2017 -- Source: Scopus
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MSK Authors
  1. Lorenz Studer
    221 Studer
  2. Nadja Zeltner
    9 Zeltner
  3. Mohamed Ahmed Soliman
    3 Soliman
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