Development and function of tissue resident macrophages in mice Journal Article


Authors: Kierdorf, K.; Prinz, M.; Geissmann, F.; Perdiguero, E. G.
Article Title: Development and function of tissue resident macrophages in mice
Abstract: Macrophages are important for tissue development, homeostasis as well as immune response upon injury or infection. For a long time they were only seen as one uniform group of phagocytes with a common origin and similar functions. However, this view has been challenged in the last decade and revealed a complex diversity of tissue resident macrophages. Here, we want to present the current view on macrophage development and tissue specification and we will discuss differences as well as common patterns between heterogeneous macrophage subpopulations. © 2016 Elsevier Ltd.
Keywords: nonhuman; animal experiment; histiocyte; macrophage; histogenesis; mononuclear phagocytes; erythro-myeloid progenitor; tissue specification; pulse labeling models
Journal Title: Seminars in Immunology
Volume: 27
Issue: 6
ISSN: 1044-5323
Publisher: Academic Press Inc., Elsevier Science  
Date Published: 2015-12-01
Start Page: 369
End Page: 378
Language: English
DOI: 10.1016/j.smim.2016.03.017
PROVIDER: scopus
PMCID: PMC4948121
PUBMED: 27036090
DOI/URL:
Notes: Review -- Export Date: 1 September 2017 -- Source: Scopus
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