Unshielding exosomal RNA unleashes tumor growth and metastasis Journal Article


Authors: Matei, I.; Kim, H. S.; Lyden, D.
Article Title: Unshielding exosomal RNA unleashes tumor growth and metastasis
Abstract: Reciprocal interactions between tumor cells and their microenvironment drive cancer progression and therapy resistance. In this issue, Nabet et al. demonstrate that dynamic feedback between tumor and stroma subverts normal inflammatory responses by triggering the release of exosomes containing unshielded RNAs that activate pattern recognition receptors, thereby promoting tumor growth and metastasis. © 2017
Journal Title: Cell
Volume: 170
Issue: 2
ISSN: 0092-8674
Publisher: Cell Press  
Date Published: 2017-07-13
Start Page: 223
End Page: 225
Language: English
DOI: 10.1016/j.cell.2017.06.047
PROVIDER: scopus
PUBMED: 28708994
DOI/URL:
Notes: Short Survey -- Export Date: 2 August 2017 -- Source: Scopus
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  1. David C Lyden
    87 Lyden