Palatal botulinum toxin as a novel therapy for objective tinnitus in forced eyelid closure syndrome Journal Article


Authors: Kaffenberger, T. M.; Mandal, R.; Schaitkin, B. M.; Hirsch, B. E.
Article Title: Palatal botulinum toxin as a novel therapy for objective tinnitus in forced eyelid closure syndrome
Abstract: Objective tinnitus associated with eyelid closure is a rare clinical entity with only a few reported cases. This association previously was identified as forced eyelid closure syndrome (FECS) and involves an aberrant neural reflex between cranial nerve VII (activating the orbicularis oculi muscle) and cranial nerve V (activating the tensor tympani muscle). We present a 52-year-old Caucasian female with a 2-month history of FECS who was successfully treated with intrapalatal botulinum toxin, with full resolution of her objective tinnitus symptoms. This is the first reported use of botulinum toxin in FECS. Laryngoscope, 127:1199–1201, 2017. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.
Keywords: middle aged; case report; pathophysiology; tinnitus; syndrome; muscle relaxant agent; facial nerve; palate; botulinum toxin a; botulinum toxin; trigeminal nerve; eyelids; humans; human; female; eyelid; fecs; objective tinnitus; palatal tinnitus; botulinum toxins, type a; neuromuscular agents
Journal Title: Laryngoscope
Volume: 127
Issue: 5
ISSN: 0023-852X
Publisher: Wiley Blackwell  
Date Published: 2017-05-01
Start Page: 1199
End Page: 1201
Language: English
DOI: 10.1002/lary.26191
PUBMED: 27717035
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 3 July 2017 -- Source: Scopus
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  1. Rajarsi   Mandal
    8 Mandal