Does pyloric drainage have a role in the era of minimally invasive esophagectomy? Journal Article


Authors: Nobel, T.; Tan, K. S.; Barbetta, A.; Adusumilli, P.; Bains, M.; Bott, M.; Jones, D.; Molena, D.
Article Title: Does pyloric drainage have a role in the era of minimally invasive esophagectomy?
Abstract: Introduction: Pyloric drainage during minimally invasive esophagectomy (MIE) may be more technically challenging than with an open approach. Alternatives to classic surgical drainage have increased in popularity; however, data are lacking to demonstrate whether one technique is superior in MIE. The purpose of this study was to compare post-operative outcomes after MIE between different pyloric drainage methods. Methods: We performed a retrospective review of a prospectively maintained database of patients undergoing MIE at a single academic institution. Patients were divided into three groups for analysis: no drainage, intrapyloric Botulinum Toxin injection, and surgical drainage (pyloroplasty or pyloromyotomy). The primary outcome was any complication within 90 days of surgery; secondary outcomes included reported symptoms and need for pyloric dilation at 6 and 12 months post-operatively. Comparisons among groups were conducted using the Kruskal Wallis and Chi Square tests. Results: There were 283 MIE performed between 2011 and 2017; of these, 126 (45%) had drainage (53 Botulinum injection and 73 surgical). No significant difference in the rate of post-operative complications, pneumonia, or anastomotic leak was observed between groups. At 6 and 12 months, patients that received Botulinum injection and surgical drainage had significantly more symptoms than no drainage (p < 0.0001) and higher need for pyloric dilation at 6 months (p = 0.007). Conclusions: Pyloric drainage was not significantly associated with lower post-operative complications or long-term symptoms. While Botulinum injection appears safe post-operatively, it was associated with increased morbidity long-term. Pyloric drainage in MIE may be unnecessary. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Keywords: esophagectomy; post-operative complications; pyloric drainage; pyloric stricture
Journal Title: Surgical Endoscopy
Volume: 33
Issue: 10
ISSN: 0930-2794
Publisher: Springer  
Date Published: 2019-10-01
Start Page: 3218
End Page: 3227
Language: English
DOI: 10.1007/s00464-018-06607-8
PUBMED: 30535543
PROVIDER: scopus
PMCID: PMC6557699
DOI/URL:
Notes: Source: Scopus
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MSK Authors
  1. Matthew Bott
    135 Bott
  2. Manjit S Bains
    338 Bains
  3. David Randolph Jones
    417 Jones
  4. Daniela   Molena
    271 Molena
  5. Kay See   Tan
    241 Tan
  6. Tamar B Nobel
    42 Nobel