Fungal disease in the immunocompromised host Journal Article


Authors: Myskowski, P. L.; White, M. H.; Ahkami, R.
Article Title: Fungal disease in the immunocompromised host
Abstract: A variety of superficial and deep mycoses may affect the immunocompromised patient. Among the superficial mycoses, candidal infections are common in all groups, but dermatophyte and pityrosporum infections may also be found. Although not primarily dangerous, they may lead to secondary bacterial infections and morbidity. Of the systemic mycoses, candidiasis, aspergillosis, and mucormycosis are frequently lethal and require early diagnosis and aggressive antifungal treatment. Endemic mycoses, such as histoplasmosis and coccidioidomycosis, may result in severe and often fatal infections in those patients with cellular immune alterations. The identification and prophylaxis of high-risk patients and the development of more effective antifungal therapies are beginning to have an impact on the control of fungal disease in this population.
Keywords: survival rate; review; human immunodeficiency virus infection; risk factors; early diagnosis; acquired immune deficiency syndrome; ketoconazole; immunocompromised host; bacterial infection; fluconazole; mycosis; infection risk; intravenous drug administration; itraconazole; oral drug administration; flucytosine; coccidioidomycosis; histoplasmosis; intramuscular drug administration; potassium iodide; amphotericin b; cryptococcosis; topical drug administration; humans; human; priority journal; pyrrole; selenium sulfide; dermatomycosis; mucormycosis; penicillium marneffei; sporotrichosis; dermatomycoses
Journal Title: Dermatologic Clinics
Volume: 15
Issue: 2
ISSN: 0733-8635
Publisher: W.B. Saunders Co.  
Date Published: 1997-04-01
Start Page: 295
End Page: 305
Language: English
DOI: 10.1016/s0733-8635(05)70437-x
PUBMED: 9098638
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 17 March 2017 -- Source: Scopus
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MSK Authors
  1. Mary H White
    43 White
  2. Patricia Myskowski
    216 Myskowski