Thyroid hemiagenesis Journal Article


Authors: Shaha, A. R.; Gujarati, R.
Article Title: Thyroid hemiagenesis
Abstract: Background and Objectives: Thyroid hemiagenesis is a rare embryological condition, predominantly in females (3:1) with a left lobe being absent. The associated diseases in the remaining thyroid lobe include benign adenoma, multinodular goiter, hyperthyroidism, chronic thyroidiris, and rarely carcinoma. The most common pathology involved in thyroid hemiagenesis is hyperthyroidism. Presence of carcinoma in a patient with hemiagenesis is quite rare and very few cases are reported in the world literature. Methods: We report a 30-year-old female who presented with left thyroid mass gradually increasing in size over a period of 3 months. The patient's pre-operative workup included a thyroid scan, which revealed a cold nodule in the left lobe with absent right lobe. A fine-needle aspiration biopsy was suspicious for papillary thyroid carcinoma. The patient underwent thyroid exploration and left thyroid lobectomy. Results: The operative findings confirmed hemiagenesis of the right lobe and papillary carcinoma in the left lobe. All four parathyroids were in normal position. The purpose of this presentation is to discuss and review the literature on thyroid hemiagenesis and present a rare case of absent right thyroid lobe with carcinoma in the remaining left thyroid lobe.
Keywords: adult; case report; carcinoma, papillary; thyroid carcinoma; thyroid neoplasms; hyperthyroidism; aspiration biopsy; thyroid gland; thyroid disease; thyroid scintiscanning; goiter; thyroiditis; embryopathy; agenesis; thyroid adenoma; humans; human; female; priority journal; article; thyroid cancerembryologic anomaly
Journal Title: Journal of Surgical Oncology
Volume: 65
Issue: 2
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 1997-06-01
Start Page: 137
End Page: 140
Language: English
DOI: 10.1002/(sici)1096-9098(199706)65:2<137::aid-jso12>3.0.co;2-2
PUBMED: 9209527
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Ashok R Shaha
    697 Shaha