Primary pulmonary osteosarcoma: A report of 4 cases and a review of the literature Journal Article


Authors: Shenjere, P.; Travis, W. D.; Franks, T. J.; Doran, H. M.; Hasleton, P. S.
Article Title: Primary pulmonary osteosarcoma: A report of 4 cases and a review of the literature
Abstract: Primary pulmonary osteosarcoma is very rare. Most cases are secondary deposits from primaries arising in the appendicular skeleton. Four cases of primary osteogenic sarcoma of the lung are described and the literature reviewed for previously reported cases. These pulmonary tumors occur in patients who are in their fourth to seventh decades, that is, an older age group than their primary bone equivalent. There is a slight male predominance. There appears to be a propensity for the left lung, especially the left upper lobe. The clinical presentation is similar to primary (epithelial) lung cancer. Differentiation from pleomorphic carcinomas and other sarcomas is discussed. We know of no predisposing factor(s) in our cases for the development of this tumor. © The Author(s) 2011.
Keywords: osteosarcoma; adult; human tissue; aged; histopathology; case report; hypertension; cancer radiotherapy; computer assisted tomography; lung lobectomy; lung cancer; coughing; thorax pain; death; peripheral vascular disease; thorax radiography; ossification; hypercholesterolemia; spindle cell sarcoma; frozen section; lung biopsy; bone necrosis; bone scintiscanning; spine metastasis; hemoptysis; carpal tunnel syndrome; angina pectoris; primary pulmonary osteosarcoma; chest infection; fiberoptic bronchoscopy
Journal Title: International Journal of Surgical Pathology
Volume: 19
Issue: 2
ISSN: 1066-8969
Publisher: Sage Publications  
Date Published: 2011-04-01
Start Page: 225
End Page: 229
Language: English
DOI: 10.1177/1066896909332382
PROVIDER: scopus
PUBMED: 19282294
DOI/URL:
Notes: --- - "Export Date: 23 June 2011" - "CODEN: IJSPF" - "Source: Scopus"
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  1. William D Travis
    743 Travis