Epidermoid tumors of the temporal lobe as epileptogenic foci Journal Article
| Authors: | Hanft, S. J.; Komotar, R. J.; Raper, D. M. S.; Sisti, M. B.; McKhann, G. M. 2nd |
| Article Title: | Epidermoid tumors of the temporal lobe as epileptogenic foci |
| Abstract: | Intracerebral epidermoid tumors of the temporal lobe are exceedingly rare. The vast majority of these slow-growing tumors remain clinically silent while only a select few are associated with overt symptomatology. We report two patients with epidermoid tumors whose unique location in the temporal lobe resulted in secondarily generalized seizures. Our first patient, a 19-year-old female, presented with a secondarily generalized tonic-clonic seizure and MRI revealed a superior temporal lobe lesion that was subsequently treated with an awake craniotomy and gross total resection. Our second patient was a 71-year-old male with a recent seizure history and known left temporal lobe lesion. The patient underwent craniotomy for gross total resection of the mass. In these two patients, we found that MRI proved diagnostic and surgical resection was curative. Our clinical experience and review of the literature indicate that gross total resection of these lesions confers control of localization-related epilepsy. © 2011 Elsevier Masson SAS. All rights reserved. |
| Keywords: | adult; aged; young adult; histopathology; review; case report; postoperative period; outcome assessment; brain tumor; follow up; brain neoplasms; follow-up studies; tumor localization; differential diagnosis; grand mal seizure; temporal lobe; tonic clonic seizure; recurrent disease; teratoma; oligodendroglioma; craniotomy; epilepsy; giant cell; diffusion weighted imaging; brain surgery; epileptic focus; epidermoid; brain abscess; epidermoid tumor; squamous epithelium; epidermal cyst; epilepsy, temporal lobe |
| Journal Title: | Journal of Clinical Neuroscience |
| Volume: | 18 |
| Issue: | 10 |
| ISSN: | 0967-5868 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2011-10-01 |
| Start Page: | 1396 |
| End Page: | 1399 |
| Language: | English |
| DOI: | 10.1016/j.jocn.2011.03.001 |
| PROVIDER: | scopus |
| PUBMED: | 21802304 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "CODEN: JCNUE" - "Source: Scopus" |
