Localization of the human HuR gene to chromosome 19p13.2 Journal Article
| Authors: | Ma, W. J.; Furneaux, H. |
| Article Title: | Localization of the human HuR gene to chromosome 19p13.2 |
| Abstract: | The HuR gene encodes a specific RNA binding protein that is a member of the human Elav-like gene family. This family of proteins, which includes HuD, HuC and Hel-N1, is involved in cellular differentiation. Alterations of HuD and Hel-N1 structure are associated with small cell lung tumors and medulloblastomas. To investigate a possible linkage of the HuR gene to malignancy, the locus of the gene was mapped on human metaphase chromosomes. Analysis of the fluorescence signals on banded chromosomes showed that the HuR gene is localized to human chromosome 19p13.2. |
| Keywords: | human cell; cells, cultured; in situ hybridization, fluorescence; rna binding protein; rna-binding proteins; chromosomes, human, pair 19; lymphocytes; karyotyping; fluorescence analysis; gene location; antigens, surface; chromosome mapping; multigene family; chromosome 19p; metaphase chromosome; chromosome banding pattern; humans; human; priority journal; article; human genetics |
| Journal Title: | Human Genetics |
| Volume: | 99 |
| Issue: | 1 |
| ISSN: | 0340-6717 |
| Publisher: | Springer |
| Date Published: | 1997-01-01 |
| Start Page: | 32 |
| End Page: | 33 |
| Language: | English |
| DOI: | 10.1007/s004390050305 |
| PUBMED: | 9003489 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 17 March 2017 -- Source: Scopus |
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