Quantitative methanol-burning lung model for validating gas-exchange- measurements over wide ranges of FI(O2) Journal Article
| Authors: | Miodownik, S.; Melendez, J.; Arslan Carlon, V.; Burda, B. |
| Article Title: | Quantitative methanol-burning lung model for validating gas-exchange- measurements over wide ranges of FI(O2) |
| Abstract: | The methanol-burning lung model has been used as a technique for generating a predictable ratio of carbon dioxide production (V̇CO2) to oxygen consumption (V̇O2) or respiratory quotient (RQ). Although an accurate RQ can be generated, quantitatively predictable and adjustable V̇O2 and V̇CO2 cannot be generated. We describe a new burner device in which the combustion rate of methanol is always equal to the infusion rate of fuel over an extended range of O2 concentrations. This permits the assembly of a methanol-burning lung model that is usable with O2 concentrations up to 100% and provides continuously adjustable and quantitative V̇O2 (691,525 ml/min) and V̇CO2 (46-1,016 ml/min) at a RQ of 0.667. |
| Keywords: | metabolism; models, biological; oxygen; device; measurement; lung; oxygen consumption; carbon dioxide; methanol; calorimetry; respiratory function tests; priority journal; article; pulmonary gas exchange; lung gas exchange; indirect calorimetry; calorimetry, indirect; carbon dioxide production; lung model; respiratory quotient; fuel; combustion |
| Journal Title: | Journal of Applied Physiology |
| Volume: | 84 |
| Issue: | 6 |
| ISSN: | 8750-7587 |
| Publisher: | American Physiological Society |
| Date Published: | 1998-06-01 |
| Start Page: | 2177 |
| End Page: | 2182 |
| Language: | English |
| PUBMED: | 9609815 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 12 December 2016 -- Source: Scopus |
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