Squamous cell carcinoma of the tongue in young patients: A matched-pair analysis Journal Article
| Authors: | Friedlander, P. L.; Schantz, S. P.; Shaha, A. R.; Yu, G.; Shah, J. P. |
| Article Title: | Squamous cell carcinoma of the tongue in young patients: A matched-pair analysis |
| Abstract: | Background. Tongue cancer is seen with increasing frequency in young individuals. There is controversy concerning the clinical course and outcome for oral tongue cancer in young patients. Methods. A retrospective review of 36 patients under 40 years of age with squamous cell carcinoma of the tongue was performed. These patients were matched to an older populations. The 5- year disease-free survival; rates of local, regional, and distant failure; and rate of second primary tumor were determined for both populations. Results. The 5-year disease-free survival for the young patients was 62% versus in the older population (p = .30). Ten of 36 (28%) of younger patients recurred locally versus five of 36 (14%) of the older patients (p = .11). Nine of 36 (25%) younger patients recurred regionally in the younger group versus six of 36 (17%) patients in the older group (p = .25). Sixteen of 36 (44%) of the younger patients had locoregional failure versus eight of 36 (22%) of the older patients (p < .05). The rates of metastatic disease and second primary lesions were similar in both populations. Conclusions. In this series, younger patients with squamous cell carcinoma of the oral tongue had a rate of locoregional recurrence rate than did older patients. This did not translate into a survival difference. |
| Keywords: | survival; adult; cancer survival; clinical article; controlled study; survival analysis; treatment failure; cancer recurrence; cigarette smoking; squamous cell carcinoma; carcinoma, squamous cell; cancer risk; cancer staging; follow up; neoplasm staging; demography; metastasis; neoplasm recurrence, local; age factors; tongue cancer; tongue neoplasms; young patients; matched-pair analysis; tongue carcinoma; humans; prognosis; human; priority journal; article |
| Journal Title: | Head & Neck |
| Volume: | 20 |
| Issue: | 5 |
| ISSN: | 1043-3074 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 1998-08-01 |
| Start Page: | 363 |
| End Page: | 368 |
| Language: | English |
| DOI: | 10.1002/(sici)1097-0347(199808)20:5<363::aid-hed1>3.0.co;2-w |
| PUBMED: | 9663661 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 12 December 2016 -- Source: Scopus |
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