Liver resection for metastatic colorectal leiomyosarcoma: A single center experience Journal Article


Authors: Faraj, W.; El-Kehdy, J.; Nounou, G. E.; Deeba, S.; Fakih, H.; Jabbour, M.; Haydar, A.; Naaj, A. A. E.; Abou-Alfa, G. K.; O'Reilly, E. M.; Shamseddine, A.; Khalife, M.; Mukherji, D.
Article Title: Liver resection for metastatic colorectal leiomyosarcoma: A single center experience
Abstract: Background: Leiomyosarcoma arising in the colorectum is a rare malignancy of the smooth muscles accounting for less than 1% of gastrointestinal tumors. Surgery remains the most accepted modality for the treatment of this entity however management of liver metastases remains controversial. Methods & results: From 1998 to 2009, five patients diagnosed with primary leiomyosarcoma of colorectal origin with metastatic liver disease, underwent liver resections at the American University of Beirut Medical Center. The median overall survival was 47 months (range, 7-135 months). Conclusions: Leiomyosarcoma of colorectal origin with liver metastasis is a very rare entity. Long-term survival can be achieved after surgical resection and should be considered for all patients. © Journal of Gastrointestinal Oncology.
Keywords: adult; clinical article; aged; middle aged; young adult; histopathology; doxorubicin; adjuvant therapy; colorectal cancer; metastasis; computer assisted tomography; ifosfamide; abdominal pain; liver metastasis; liver; colonoscopy; colon resection; liver resection; leiomyosarcoma; cholecystectomy; hemicolectomy; liver biopsy; colon; rectum; fine needle aspiration biopsy; human; male; female; article; colorectal leiomyosarcoma
Journal Title: Journal of Gastrointestinal Oncology
Volume: 6
Issue: 5
ISSN: 2078-6891
Publisher: Pioneer Bioscience Publishing Company  
Date Published: 2015-10-01
Start Page: E70
End Page: E76
Language: English
DOI: 10.3978/j.issn.2078-6891.2015.044
PROVIDER: scopus
PMCID: PMC4570914
PUBMED: 26487954
DOI/URL:
Notes: Article -- Export Date: 6 December 2016 -- Source: Scopus
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  1. Ghassan Abou-Alfa
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  2. Eileen O'Reilly
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