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Lukas Dow

Formats
  1. Journal Article (13)
  2. Meeting Abstract (5)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (17)
  2. Cancer Biology and Genetics Program Faculty (17)
  3. Center for Hematologic Malignancies (17)
  4. Center for Molecular Imaging and Biotechnology (CMIB) (17)
  5. Center for Pancreatic Cancer Research (17)
  6. Executive Committee, Center for Hematologic Malignancies (17)

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People
  1. Scott Lowe (17)
  2. Kevin O'Rourke (5)
  3. Darjus-Felix Tschaharganeh (4)
  4. Edward Kastenhuber (3)
  5. Nilgun Tasdemir (3)
  6. Ana Tome Moita Banito (2)

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Years
  1. 2022 (1)
  2. 2021 (1)
  3. 2017 (1)
  4. 2016 (1)
  5. 2015 (3)
  6. 2014 (7)

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Publications
  1. Cell (3)
  2. Cancer Research (2)
  3. PLoS ONE (2)
  4. Proceedings of the National Academy of Sciences of the United States of America (2)
  5. BMC Pharmacology & Toxicology (1)
  6. Cell Reports (1)

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Publishers
  1. Cell Press (4)
  2. American Association for Cancer Research (3)
  3. National Academy of Sciences (2)
  4. Public Library of Science (2)
  5. American Society of Clinical Oncology (1)
  6. Biomed Central Ltd (1)

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Results (18)

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  • A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets
    Journal Article

    Li, X.; Huang, C. H.; Sánchez-Rivera, F. J.; Kennedy, M. C.; Tschaharganeh, D. F.; Morris, J. P. 4th; Montinaro, A.; O'Rourke, K. P.; Banito, A.; Wilkinson, J. E.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2022)

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  • KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix
    Journal Article

    Kim, J. K.; Marco, M. R.; Choi, S. H.; Qu, X.; Chen, C. T.; Elkabets, M.; Fairchild, L.; Chow, O.; Barriga, F. M.; Dow, L. E.; more...
    Molecular Oncology (2021)

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  • WNT signaling and colorectal cancer
    Journal Article

    Schatoff, E. M.; Leach, B. I.; Dow, L. E.
    Current Colorectal Cancer Reports (2017)

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  • Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas
    Journal Article

    Ebbesen, S. H.; Scaltriti, M.; Bialucha, C. U.; Morse, N.; Kastenhuber, E. R.; Wen, H. Y.; Dow, L. E.; Baselga, J.; Lowe, S. W.
    Proceedings of the National Academy of Sciences of the United States of America (2016)

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  • KRAS mutation in colorectal cancer and its association with a stromal-derived gene signature
    Meeting Abstract

    Pelossof, R.; Elkabets, M.; Chow, O.S.; Fairchild, L.; Chen, C. T.; Setty, M.; Smith, J. J.; Dow, L. E.; O'Rourke, K. P.; Lowe, S. W.; more...
    Journal of Clinical Oncology (2015)

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  • Apc restoration promotes cellular differentiation and reestablishes crypt homeostasis in colorectal cancer
    Journal Article

    Dow, L. E.; O'Rourke, K. P.; Simon, J.; Tschaharganeh, D. F.; van Es, J. H.; Clevers, H.; Lowe, S. W.
    Cell (2015)

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  • Inducible in vivo genome editing with CRISPR-Cas9
    Journal Article

    Dow, L. E.; Fisher, J.; O'Rourke, K. P.; Muley, A.; Kastenhuber, E. R.; Livshits, G.; Tschaharganeh, D. F.; Socci, N. D.; Lowe, S. W.
    Nature Biotechnology (2015)

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  • RNAi mouse models: Revolutionizing drug discovery in vivo
    Meeting Abstract

    Premsrirut, P.; Dow, L.; Hannon, G.; Zuber, J.; Lowe, S.; Zender, L.; Fellmann, C.
    Molecular Cancer Research (2014)

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  • RNAi mouse models: Revolutionizing drug discovery in vivo
    Meeting Abstract

    Premsrirut, P. K.; Yoon, B.; Pesic, M.; Dow, L. E.; Zuber, J.; Lowe, S. W.; Hannon, G. J.; Zender, L.; Fellmann, C.
    Cancer Research (2014)

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  • Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition
    Meeting Abstract

    Bolden, J.; Tasdemir, N.; Dow, L.; van Es, J. H.; Wilkinson, J. E.; Zhao, Z.; Clevers, H.; Lowe, S. W.
    Cancer Research (2014)

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