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Ronnie Maharaj

Formats
  1. Journal Article (5)
  2. Meeting Abstract (3)
Groups
  1. Center for Hematologic Malignancies (8)
  2. GSK Faculty (8)
  3. Hematologic Malignancies Research (8)
  4. Molecular Pharmacology and Chemistry Program Faculty (8)
  5. Sloan Kettering Institute Faculty (8)
  6. Sloan Kettering Institute Postdocs (8)
People
  1. Gabriela Chiosis (8)
  2. Alexander Gozman (7)
  3. Anna Rodina Balingcongan (7)
  4. Tony Taldone (7)
  5. Yanlong Kang (7)
  6. Cristina Clement (4)

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Years
  1. 2015 (1)
  2. 2014 (2)
  3. 2013 (1)
  4. 2011 (2)
  5. 2010 (1)
  6. 2008 (1)
Publications
  1. Cancer Research (2)
  2. ACS Chemical Biology (1)
  3. Abstracts of Papers of the American Chemical Society (1)
  4. Assay and Drug Development Technologies (1)
  5. Chemistry and Biology (1)
  6. Current Opinion in Pharmacology (1)

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Publishers
  1. American Chemical Society (3)
  2. American Association for Cancer Research (2)
  3. Elsevier Inc. (2)
  4. Mary Ann Liebert, Inc (1)

Results (8)

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  • Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells
    Meeting Abstract

    Rodina, A. A.; Taldone, T.; Kang, Y. L.; Patel, P.; Koren, J.; Yan, P.; DaGama Gomes, E.; Yang, C.; Patel, M.; Shrestha, L.; more...
    Cancer Research (2015)

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  • Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer
    Journal Article

    Rodina, A.; Taldone, T.; Kang, Y.; Patel, P. D.; Koren, J.; Yan, P.; DaGama Gomes, E. M.; Yang, C.; Patel, M. R.; Shrestha, L.; more...
    ACS Chemical Biology (2014)

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  • Heat shock protein 70 inhibitors. 2. 2,5′-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70
    Journal Article

    Taldone, T.; Kang, Y.; Patel, H. J.; Patel, M. R.; Patel, P. D.; Rodina, A.; Patel, Y.; Gozman, A.; Maharaj, R.; Clement, C. C.; more...
    Journal of Medicinal Chemistry (2014)

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  • Identification of an allosteric pocket on human Hsp70 reveals a mode of inhibition of this therapeutically important protein
    Journal Article

    Rodina, A.; Patel, P. D.; Kang, Y.; Patel, Y.; Baaklini, I.; Wong, M. J. H.; Taldone, T.; Yan, P.; Yang, C.; Maharaj, R.; more...
    Chemistry and Biology (2013)

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  • YK5 is a novel dual Hsc/Hsp70 inhibitor that is selective for tumor Hsp70 and is a valuable lead for the development of molecules with therapeutic potential in breast cancer
    Meeting Abstract

    Taldone, Tony; Kang, Yanlong; Rodina, Anna; Maharaj, Ronnie; Gozman, Alexander; Cerchietti, Leandro; Wong, Michael J. H.; Baaklini, Imad; Caldas Lopes, Eloisi; Patel, Hardik J.; more...
    Abstracts of Papers of the American Chemical Society (2011)

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  • Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators
    Journal Article

    Ahn, J. H.; Luo, W.; Kim, J.; Rodina, A.; Clement, C. C.; Aguirre, J.; Sun, W.; Kang, Y.; Maharaj, R.; Moulick, K.; more...
    Assay and Drug Development Technologies (2011)

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  • YK5, a novel dual Hsc70 and Hsp70 inhibitor, is selective for tumor Hsp70 and has potent but selective activity in cancer cells
    Meeting Abstract

    Rodina, A.; Kang, Y.; Maharaj, R.; Gozman, A.; Taldone, T.; Cerchietti, L.; Wong, M. J. H.; Baaklini, I.; Caldas-Lopes, E.; Clement, C. C.; more...
    Cancer Research (2010)

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  • Targeting Hsp90: Small-molecule inhibitors and their clinical development
    Journal Article

    Taldone, T.; Gozman, A.; Maharaj, R.; Chiosis, G.
    Current Opinion in Pharmacology (2008)

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