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Ensar Halilovic

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Meeting Abstract (7)
  2. Journal Article (4)
Groups
  1. Breast Medicine Service (11)
  2. Department of Medicine (11)
  3. GSK Faculty (11)
  4. Genitourinary Oncology Service (11)
  5. Human Oncology and Pathogenesis Program (11)
  6. Molecular Pharmacology and Chemistry Program Faculty (11)

More Groups

People
  1. David Solit (11)
  2. Neal Rosen (11)
  3. Christine Pratilas (7)
  4. Ayana Sawai (4)
  5. Yogindra Persaud (4)
  6. Barry Taylor (3)

More People

Years
  1. 2010 (4)
  2. 2009 (1)
  3. 2008 (3)
  4. 2007 (3)
Publications
  1. Cancer Research (7)
  2. Cancer Cell (1)
  3. Journal of Clinical Oncology (1)
  4. Molecular Cancer Therapeutics (1)
  5. Proceedings of the National Academy of Sciences of the United States of America (1)
Publishers
  1. American Association for Cancer Research (8)
  2. American Society of Clinical Oncology (1)
  3. Cell Press (1)
  4. National Academy of Sciences (1)

Results (11)

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  • The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner
    Meeting Abstract

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Persaud, Y.; Xing, F.; Halilovic, E.; Viale, A.; more...
    Cancer Research (2010)

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  • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors
    Journal Article

    She, Q. B.; Halilovic, E.; Ye, Q.; Zhen, W.; Shirasawa, S.; Sasazuki, T.; Solit, D. B.; Rosen, N.
    Cancer Cell (2010)

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  • The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
    Journal Article

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Halilovic, E.; Persaud, Y.; Xing, F.; Viale, A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2010)

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  • PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling
    Journal Article

    Halilovic, E.; She, Q. B.; Ye, Q.; Pagliarini, R.; Sellers, W. R.; Solit, D. B.; Rosen, N.
    Cancer Research (2010)

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  • Identification and biological characterization of exon 4 KRAS mutations by MALDI-TOF Mass Spectrometry based genotyping
    Meeting Abstract

    Janakiraman, M.; Zeng, Z.; Chitale, D.; Halilovic, E.; Rosen, N.; Vakiani, E.; Heguy, A.; Ladanyi, M.; Jhanwar, S.; Saltz, L.; more...
    Cancer Research (2009)

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  • PLX4032, a selective inhibitor of RAF kinase activity, inhibits BRAF(V600E) tumor proliferation and MAPK signaling in vitro and in vivo
    Meeting Abstract

    Joseph, E. W.; Poulikakos, P. I.; Pratilas, C. A.; Halilovic, E.; Lobo, J. M.; Bollag, G.; Tsai, J.; Solit, D. B.; Rosen, N.
    Cancer Research (2008)

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  • Coexistent PI3K mutation in human tumors is associated with decreased dependency on mutant KRAS and MEK/ERK signaling for transformation
    Meeting Abstract

    Halilovic, E.; She, Q.; Ye, Q.; Solit, D. B.; Rosen, N.
    Cancer Research (2008)

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  • Genetic predictors of MEK dependence in non-small cell lung cancer
    Journal Article

    Pratilas, C. A.; Hanrahan, A. J.; Halilovic, E.; Persaud, Y.; Soh, J.; Chitale, D.; Shigematsu, H.; Yamamoto, H.; Sawai, A.; Janakiraman, M.; more...
    Cancer Research (2008)

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  • BRAF mutation predicts MEK-dependence in non-small cell lung cancer (NSCLC)
    Meeting Abstract

    Pratilas, C. A.; Halilovic, E.; Sawai, A.; Grbovic-Huezo, O.; Rosen, N.; Solit, D. B.
    Journal of Clinical Oncology (2007)

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  • BRAF mutation predicts for MEK-dependence in non-small cell lung cancer (NSCLC)
    Meeting Abstract

    Halilovic, E.; Pratilas, C.; Sawai, A.; Grbovic, O.; Rosen, N.; Solit, D. B.
    Cancer Research (2007)

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