The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner Meeting Abstract


Authors: Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Persaud, Y.; Xing, F.; Halilovic, E.; Viale, A.; Chapman, P.; Tsai, J.; Bollag, G.; Rosen, N.; Solit, D. B.
Abstract Title: The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner
Meeting Title: 101st Annual Meeting of the American Association for Cancer Research (AACR)
Keywords: biochemistry and molecular biophysics; tumor biology; pharmacology; cell proliferation, biochemical pathway
Journal Title: Cancer Research
Volume: 70
Issue: 8 Suppl.
Meeting Dates: 2010 Apr 17-21
Meeting Location: Washington, DC
ISSN: 0008-5472
Publisher: American Association for Cancer Research  
Date Published: 2010-04-15
Start Page: 611
Language: English
ACCESSION: BIOSIS:PREV201000523386
PROVIDER: biosis
DOI: 10.1158/1538-7445.AM10-2521
Notes: --- - Meeting Abstract: 2521 - In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research - Washington, DC, USA - April 17 -21, 2010 - Amer Assoc Canc Res - "Source: Biosis"
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MSK Authors
  1. Neal Rosen
    425 Rosen
  2. David Solit
    779 Solit
  3. Paul Chapman
    326 Chapman
  4. Madhavi Tadi
    11 Tadi
  5. Agnes Viale
    245 Viale
  6. Feng Xing
    8 Xing
  7. Wei-Qing Wang
    10 Wang
  8. Barry Stephen Taylor
    238 Taylor
  9. Yogindra Paul Persaud
    14 Persaud
  10. Eric William Joseph
    13 Joseph