PLX4032, a selective inhibitor of RAF kinase activity, inhibits BRAF(V600E) tumor proliferation and MAPK signaling in vitro and in vivo Meeting Abstract
| Authors: | Joseph, E. W.; Poulikakos, P. I.; Pratilas, C. A.; Halilovic, E.; Lobo, J. M.; Bollag, G.; Tsai, J.; Solit, D. B.; Rosen, N. |
| Abstract Title: | PLX4032, a selective inhibitor of RAF kinase activity, inhibits BRAF(V600E) tumor proliferation and MAPK signaling in vitro and in vivo |
| Meeting Title: | 99th Annual Meeting of the American Association for Cancer Research (AACR) |
| Keywords: | cell proliferation; biochemical pathway; feedback inhibition |
| Journal Title: | Cancer Research |
| Volume: | 68 |
| Issue: | 9 Suppl. |
| Meeting Dates: | 2008 Apr 12-16 |
| Meeting Location: | San Diego, CA |
| ISSN: | 0008-5472 |
| Publisher: | American Association for Cancer Research |
| Date Published: | 2008-05-01 |
| Start Page: | 815 |
| Language: | English |
| ACCESSION: | BIOSIS:PREV200800487704 |
| PROVIDER: | biosis |
| DOI/URL: | |
| Notes: | --- - Meeting Abstract: 3437 - Poster Presentation - In: Proceedings of the 99th Annual Meeting of the American Association for Cancer Research - San Diego, CA, USA - April 12 -16, 2008 - Amer Assoc Canc Res - "Source: Biosis" |
