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Yogindra Paul Persaud

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Meeting Abstract (7)
  2. Journal Article (3)
Groups
  1. Breast Medicine Service (10)
  2. Department of Medicine (10)
  3. GSK Faculty (10)
  4. Genitourinary Oncology Service (10)
  5. Human Oncology and Pathogenesis Program (10)
  6. Molecular Pharmacology and Chemistry Program Faculty (10)

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People
  1. David Solit (10)
  2. Neal Rosen (10)
  3. Manickam Janakiraman (8)
  4. Christine Pratilas (7)
  5. Poulikos Poulikakos (6)
  6. Paul Chapman (5)

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Years
  1. 2012 (2)
  2. 2011 (2)
  3. 2010 (3)
  4. 2009 (1)
  5. 2008 (1)
  6. 2007 (1)
Publications
  1. Cancer Research (6)
  2. European Journal of Cancer (1)
  3. Molecular Cancer Therapeutics (1)
  4. Nature (1)
  5. Proceedings of the National Academy of Sciences of the United States of America (1)
Publishers
  1. American Association for Cancer Research (7)
  2. Elsevier Inc. (1)
  3. National Academy of Sciences (1)
  4. Nature Publishing Group (1)

Results (10)

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  • RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Kong, X.; Ng, C.; Moriceau, G.; Shi, H.; Atefi, M.; Titz, B.; Gabay, M. T.; more...
    Cancer Research (2012)

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  • Resistance to RAF inhibitors due to RAS-independent dimerization of BRAF(V600E) splicing variants
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Gabay, M. T.; Dahlman, K. B.; Sosman, J. A.; Ribas, A.; Lo, R. S.; Rosen, N.; Solit, D. B.
    European Journal of Cancer (2012)

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  • An in-frame deletion in the N-terminal regulatory domain of BRAF(V600E) causes resistance to the RAF inhibitor PLX4032
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Gabay, M. T.; Janakiraman, M.; Joseph, E. W.; Pratilas, C. A.; Chapman, P. B.; Rosen, N.; Solit, D. B.
    Cancer Research (2011)

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  • RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
    Journal Article

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Kong, X.; Ng, C.; Moriceau, G.; Shi, H.; Atefi, M.; Titz, B.; Gabay, M. T.; more...
    Nature (2011)

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  • Concurrent loss of PTEN and RB is sufficient to confer BRAF independence in melanomas harboring V600E BRAF mutations
    Meeting Abstract

    Xing, F.; Persaud, Y.; Pratilas, C.; Janakiraman, M.; She, Q. B.; Liu, C.; Dolgalev, I.; Heguy, A.; Wolchok, J.; Cobrinik, D.; more...
    Cancer Research (2010)

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  • The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner
    Meeting Abstract

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Persaud, Y.; Xing, F.; Halilovic, E.; Viale, A.; more...
    Cancer Research (2010)

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  • The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
    Journal Article

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Halilovic, E.; Persaud, Y.; Xing, F.; Viale, A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2010)

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  • Genetic predictors of MEK dependence in V600E BRAF mutant melanoma
    Meeting Abstract

    Xing, F.; Pratilas, C.; Persaud, Y.; Janakiraman, M.; Houghton, A.; Rosen, N.; Solit, D.
    Cancer Research (2009)

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  • Genetic predictors of MEK dependence in non-small cell lung cancer
    Journal Article

    Pratilas, C. A.; Hanrahan, A. J.; Halilovic, E.; Persaud, Y.; Soh, J.; Chitale, D.; Shigematsu, H.; Yamamoto, H.; Sawai, A.; Janakiraman, M.; more...
    Cancer Research (2008)

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  • BRAF mutation predicts MEK-dependence in non-small cell lung cancer (NSCLC)
    Meeting Abstract

    Pratilas, C. A.; Halilovic, E.; Persaud, Y.; Sawai, A.; Grbovic-Huezo, O.; Janakiraman, M.; Rosen, N.; Solit, D. B.
    Molecular Cancer Therapeutics (2007)

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