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Yogindra Paul Persaud

Formats
  1. Meeting Abstract (8)
  2. Journal Article (6)
Groups
  1. Department of Medicine (14)
  2. GSK Faculty (14)
  3. Human Oncology and Pathogenesis Program (14)
  4. Genitourinary Oncology Service (13)
  5. Solid Tumor Oncology Division (13)
  6. Sloan Kettering Institute Faculty (11)

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People
  1. David Solit (13)
  2. Manickam Janakiraman (11)
  3. Christine Pratilas (10)
  4. Neal Rosen (10)
  5. Barry Taylor (8)
  6. Feng Xing (6)

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Years
  1. 2015 (1)
  2. 2012 (3)
  3. 2011 (3)
  4. 2010 (4)
  5. 2009 (1)
  6. 2008 (1)

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Publications
  1. Cancer Research (8)
  2. Cancer Discovery (1)
  3. European Journal of Cancer (1)
  4. Molecular Cancer Therapeutics (1)
  5. Nature (1)
  6. Oncogene (1)

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Publishers
  1. American Association for Cancer Research (10)
  2. Nature Publishing Group (2)
  3. Elsevier Inc. (1)
  4. National Academy of Sciences (1)

Results (14)

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  • NF2 loss promotes oncogenic RAS-induced thyroid cancers via YAP-dependent transactivation of RAS proteins and sensitizes them to MEK inhibition
    Journal Article

    Garcia-Rendueles, M. E. R.; Ricarte-Filho, J. C.; Untch, B. R.; Landa, I.; Knauf, J. A.; Voza, F.; Smith, V. E.; Ganly, I.; Taylor, B. S.; Persaud, Y.; more...
    Cancer Discovery (2015)

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  • RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Kong, X.; Ng, C.; Moriceau, G.; Shi, H.; Atefi, M.; Titz, B.; Gabay, M. T.; more...
    Cancer Research (2012)

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  • Resistance to RAF inhibitors due to RAS-independent dimerization of BRAF(V600E) splicing variants
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Gabay, M. T.; Dahlman, K. B.; Sosman, J. A.; Ribas, A.; Lo, R. S.; Rosen, N.; Solit, D. B.
    European Journal of Cancer (2012)

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  • Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600E BRAF
    Journal Article

    Xing, F.; Persaud, Y.; Pratilas, C. A.; Taylor, B. S.; Janakiraman, M.; She, Q. B.; Gallardo, H.; Liu, C.; Merghoub, T.; Hefter, B.; more...
    Oncogene (2012)

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  • Loss of the PTEN and RB1 tumor suppressors attenuates RAF-dependence in melanomas
    Meeting Abstract

    Xing, F.; Persaud, Y.; Pratilas, C. A.; Taylor, B. S.; Janakiraman, M.; She, Q. B.; Cobrinik, D.; Solit, D. B.
    Cancer Research (2011)

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  • An in-frame deletion in the N-terminal regulatory domain of BRAF(V600E) causes resistance to the RAF inhibitor PLX4032
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Gabay, M. T.; Janakiraman, M.; Joseph, E. W.; Pratilas, C. A.; Chapman, P. B.; Rosen, N.; Solit, D. B.
    Cancer Research (2011)

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  • RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
    Journal Article

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Kong, X.; Ng, C.; Moriceau, G.; Shi, H.; Atefi, M.; Titz, B.; Gabay, M. T.; more...
    Nature (2011)

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  • Concurrent loss of PTEN and RB is sufficient to confer BRAF independence in melanomas harboring V600E BRAF mutations
    Meeting Abstract

    Xing, F.; Persaud, Y.; Pratilas, C.; Janakiraman, M.; She, Q. B.; Liu, C.; Dolgalev, I.; Heguy, A.; Wolchok, J.; Cobrinik, D.; more...
    Cancer Research (2010)

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  • The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner
    Meeting Abstract

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Persaud, Y.; Xing, F.; Halilovic, E.; Viale, A.; more...
    Cancer Research (2010)

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  • The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
    Journal Article

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Halilovic, E.; Persaud, Y.; Xing, F.; Viale, A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2010)

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