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Patrick Shea Ward

Formats
  1. Journal Article (14)
  2. Meeting Abstract (2)
Groups
  1. Sloan Kettering Institute Faculty (16)
  2. Cancer Biology and Genetics Program Faculty (15)
  3. Center for Hematologic Malignancies (15)
  4. Center for Molecular Imaging and Biotechnology (CMIB) (15)
  5. GSK Faculty (15)
  6. Hematologic Malignancies Research (15)

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People
  1. Craig Thompson (15)
  2. Chao Lu (8)
  3. Ross Levine (8)
  4. Omar Abdel-Wahab (5)
  5. Alan Shih (4)
  6. Justin Cross (4)

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Years
  1. 2017 (1)
  2. 2014 (3)
  3. 2013 (4)
  4. 2012 (6)
  5. 2011 (1)
  6. 2005 (1)
Publications
  1. Blood (2)
  2. Genes and Development (2)
  3. Nature (2)
  4. Proceedings of the National Academy of Sciences of the United States of America (2)
  5. Annals of Plastic Surgery (1)
  6. Cancer Cell (1)

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Publishers
  1. Cold Spring Harbor Laboratory Press (3)
  2. Nature Publishing Group (3)
  3. American Society of Hematology (2)
  4. Cell Press (2)
  5. National Academy of Sciences (2)
  6. American Association for Cancer Research (1)

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Results (16)

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Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia
    Journal Article

    Shih, A. H.; Meydan, C.; Shank, K.; Garrett-Bakelman, F. E.; Ward, P. S.; Intlekofer, A. M.; Nazir, A.; Stein, E. M.; Knapp, K.; Glass, J.; more...
    Cancer Discovery (2017)

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  • AG-221, a small molecule mutant IDH2 inhibitor, remodels the epigenetic state of IDH2-mutant cells and induces alterations in self-renewal/differentiation in IDH2-mutant AML model in vivo
    Meeting Abstract

    Shih, A. H.; Shank, K. R.; Meydan, C.; Intlekofer, A. M.; Ward, P.; Thompson, C. B.; Melnick, A. M.; Travins, J.; Straley, K.; Gliser, C.; more...
    Blood (2014)

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  • DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid lukemia
    Meeting Abstract

    Rampal, R. K.; Alkalin, A.; Madzo, J.; Vasanthakumar, A.; Pronier, E.; Patel, J. P.; Li, Y. S.; Ahn, J.; Abdel-Wahab, O.; Shih, A. H.; more...
    Blood (2014)

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  • DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia
    Journal Article

    Rampal, R.; Alkalin, A.; Madzo, J.; Vasanthakumar, A.; Pronier, E.; Patel, J.; Li, Y.; Ahn, J.; Abdel-Wahab, O.; Shih, A.; more...
    Cell Reports (2014)

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  • Induction of sarcomas by mutant IDH2
    Journal Article

    Lu, C.; Venneti, S.; Akalin, A.; Fang, F.; Ward, P. S.; DeMatteo, R. G.; Intlekofer, A. M.; Chen, C.; Ye, J.; Hameed, M.; more...
    Genes and Development (2013)

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  • Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition
    Journal Article

    Chen, C.; Liu, Y.; Lu, C.; Cross, J. R.; Morris, J. P. 4th; Shroff, A. S.; Ward, P. S.; Bradner, J. E.; Thompson, C.; Lowe, S. W.
    Genes and Development (2013)

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  • SnapShot: Cancer metabolism pathways
    Journal Article

    Finley, L. W. S.; Zhang, J.; Ye, J.; Ward, P. S.; Thompson, C. B.
    Cell Metabolism (2013)

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  • The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization
    Journal Article

    Ward, P. S.; Lu, C.; Cross, J. R.; Abdel-Wahab, O.; Levine, R. L.; Schwartz, G. K.; Thompson, C. B.
    Journal of Biological Chemistry (2013)

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  • Signaling in control of cell growth and metabolism
    Journal Article

    Ward, P. S.; Thompson, C. B.
    Cold Spring Harbor Perspectives in Medicine (2012)

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  • Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation
    Journal Article

    Ye, J.; Mancuso, A.; Tong, X.; Ward, P. S.; Fan, J.; Rabinowitz, J. D.; Thompson, C. B.
    Proceedings of the National Academy of Sciences of the United States of America (2012)

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