Synapse - Stewart Shuman

Results (108)

In vivo nucleotide excision repair by mycobacterial UvrD1 requires ATP hydrolysis but does not depend on cysteine disulfide-mediated dimerization and DNA unwinding

Journal Article

Warren, G. M.; Shuman, S.
Nucleic Acids Research (2025)

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Fission yeast metabolome dynamics during phosphate starvation and replenishment

Journal Article

Sanchez, A. M.; Kyaw, A. K.; Violante, S. N.; Garg, A.; Cross, J. R.; Shuman, S.
mBio (2025)

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Identification, characterization, and structure of a tRNA splicing enzyme RNA 5′-OH kinase from the pathogenic fungi Mucorales

Journal Article

Ghosh, S.; Wimberly-Gard, G.; Jacewicz, A.; Schwer, B.; Shuman, S.
RNA (2024)

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Kinetic and structural insights into the requirement of fungal tRNA ligase for a 2′-phosphate end

Journal Article

Ghosh, S.; Shuman, S.
RNA (2024)

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Chemical synthesis of 2OMeNAD(+) and its deployment as an RNA 2 -phosphotransferase (Tpt1) ‘poison’ that traps the enzyme on its abortive RNA-2 -PO(4)-(ADP-2OMe-ribose) reaction intermediate

Journal Article

Arnold, J.; Ghosh, S.; Kasprzyk, R.; Brakonier, M.; Hanna, M.; Marx, A.; Shuman, S.
Nucleic Acids Research (2024)

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Activities and genetic interactions of fission yeast Aps1, a nudix-type inositol pyrophosphatase and inorganic polyphosphatase

Journal Article

Ghosh, S.; Sanchez, A. M.; Schwer, B.; Prucker, I.; Jork, N.; Jessen, H. J.; Shuman, S.
mBio (2024)

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Structure and in vivo psoralen DNA crosslink repair activity of mycobacterial Nei2

Journal Article

Warren, G. M.; Shuman, S.
mBio (2024)

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Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1